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Kolekce v této komunitě
Poslední příspěvky
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The presence of multiple variants of IncF plasmid alleles in a single genome sequence can hinder accurate replicon sequence typing using in silico pMLST tools
původní článek
open access
postprint
2025
,mSystems
IncF plasmids are mobile genetic elements found in bacteria from the Enterobacteriaceae family and often carry critical antibiotic and virulence gene cargo. The classification of IncF plasmids using the plasmid Multi-Locus ...
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Training of English prosody with acoustically modified voices
Trénování anglické prozodie pomocí akusticky modifikovaných hlasů
původní článek
open access
vydavatelská verze
2024
,Journal of Second Language Pronunciation
,10
(3)
The paper describes an innovative training of English phrasal prosody using participants' own speech as models, with their melodic and rhythmic patterns manipulated by means of PSOLA. After the training, the participants ...
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The impact of buried historical copper slags on contemporary soil contamination
původní článek
open access
vydavatelská verze
2025
,Journal of Geochemical Exploration
,273
(June)
This study focuses on the impact of historical metallurgical slags on contemporary soil and soil pore water contamination, and potential phytoavailibility of metal(loid)s based on the example of the former smelter (16th-18th ...
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Evaluation of various membranes for blood-feeding in nine sand fly species and artificial feeding challenges in Sergentomyia minuta
původní článek
open access
vydavatelská verze
2025
,Parasites & Vectors
,18
(1)
BackgroundWe evaluated various membranes for blood-feeding in nine sand fly species from different genera and subgenera. Most of these species are vectors of human-pathogenic Leishmania, whereas Sergentomyia minuta is a ...
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Phenotypic and genotypic characterization of Candida parapsilosis complex isolates from a Lebanese hospital
původní článek
open access
postprint
2025
,Scientific Reports
,15
(1)
The opportunistic pathogen Candida parapsilosis is a major causative agent of candidiasis leading to death in immunocompromised individuals. Azoles are the first line of defense in their treatment. The purpose of this study ...
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Epigenetic Characterization of Squamous Cell Carcinoma and Mucoepidermoid Carcinoma Based on DNA Methylation Data: An In-Silico Study
abstrakt v časopisu
open access
vydavatelská verze
2025
,Oxford
,Elsevier Ltd.
,EJC Skin Cancer
,3
(S1)
Background: A recent study demonstrated that parotid squamous cell carcinomas (SCCs) are most potentially metastatic cutaneous SCCs. To define whether epigenetic alterations may explain the different molecular events between ...
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Letter to the Editor: Isolation of Carbapenemase-Producing Pseudomonas aeruginosa from a Waste-Water Sample Collected from a Greek University Hospital
letter to the editors
open access
postprint
2025
,Microbial Drug Resistance
,31
(3)
The spread of carbapenemase-producing bacteria into clinical settings has dramatically worsen the public health situation. But, also, the isolation of such organisms from samples of environmental and wildlife origin has ...
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Visual presentation of age differences in relative survival of hematological neoplasms in Sweden and the neighboring countries
původní článek
open access
vydavatelská verze
2025
,Annals of Hematology
,104
(3)
For many hematological malignancies (HMs) survival among older patients is compromised. We want to test the most up-to-date age-group-specific survival differences in five hematological malignancies, Hodgkin lymphoma (HL), ...
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Genomic analysis of extended-spectrum beta-lactamase-producing E. coli from Czech diary calves and their caretakers
původní článek
open access
postprint
2025
,Frontiers in Veterinary Science
,12
(March)
INTRODUCTION: The increasing prevalence of antimicrobial resistance in livestock, particularly the dissemination of extended-spectrum beta-lactamase-producing Escherichia coli, poses a significant zoonotic and public health ...
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Proof-of-concept MALDI-TOF-MS assay for the detection of Toxin B enzymatic activity in Clostridioides difficile infection
původní článek
open access
postprint
2025
,Microbiology Spectrum
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometers have become an integral part of all modern clinical microbiology laboratories. They serve as the key tool for pathogen identification ...
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Dietary influence and immune balance: Regulating CD4+IEL responses and MHCII in the gut
přehledový článek
omezený přístup
vydavatelská verze
2025
,Mucosal Immunology
,18
(1)
Over the past decade, interest in CD4 positive intraepithelial lymphocytes (IELs) has been growing. This subset of long-overlooked helper T cell plays critical roles in intestinal homeostasis and in responses to intestinal ...
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Pozorovací a diagnostický nástroj pro zjišťování úrovně a podoby formativního hodnocení v českých školách
Observational and Diagnostic Tool for Determining the Level and Form of Formative Assessment in Czech Schools
původní článek
open access
vydavatelská verze
2024
,Edukácia
,7
(1)
Cílem tohoto článku je shrnout stávající nástroje pro měření formativního hodnocení a vytvořit nový diagnostický a pozorovací nástroj vhodný pro vzdělávací realitu českých základních škol a nižších stupňů víceletých gymnázií ...
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Activation of the 26S Proteasome to Reduce Proteotoxic Stress and Improve the Efficacy of PROTACs
přehledový článek
open access
vydavatelská verze
2024
,ACS Pharmacology & Translational Science
,8
(1)
The 26S proteasome degrades the majority of cellular proteins and affects all aspects of cellular life. Therefore, the 26S proteasome abundance, proper assembly, and activity in different life contexts need to be precisely ...
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Alkaloids from the genus Vinca L. (Apocynaceae): a comprehensive biological and structural review
přehledový článek
open access
vydavatelská verze
2025
,Phytochemistry Reviews
,Neuveden
(29.3.2025)
This review provides a comprehensive overview of the alkaloids in the genus Vinca L. (Apocynaceae), which is renowned for its rich content of monoterpene indole alkaloids and widespread occurrence in Europe, northwest ...
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Thermally-induced release of arsenic from minerals and phases relevant to polluted natural systems affected by wildfires
původní článek
open access
vydavatelská verze
2025
,Applied Geochemistry
,182
(March)
Fire-induced arsenic (As) emission from contaminated biomass or soil is dependent on its solid-phase speciation. To quantify the nature of this release, environmentally relevant As-bearing compounds (sulfides, sulfosalts, ...
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Structural Insights and Functional Impact of the MmpL3 Inhibitor C215
abstrakt v konferenčním sborníku
open access
vydavatelská verze
2024
,Praha
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,22
(6)
Tuberculosis TB is a globally prevalent infectious disease caused by Mycobacterium tuberculosis (Mtb). We developed a straightforward synthesis of C215 and its derivatives and established a basic pharmacological profile.
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How and why does demographic decline lead to support for populist parties? The case of the Czech Republic
původní článek
open access
vydavatelská verze
2025
,Political Geography
,117
(Neuveden)
In recent decades, a strong demographic decline has characterized post-communist Central and Eastern European countries. Using the Czech Republic as a case study, we apply a multilevel structural equation model to test the ...
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Istorik–emigrant V. V. Sachaněv kak issledovatěl' Vostočnoj Slovakii i Podkarpatskoj Rusi
Ethnographer-emigrant V.V. Sachaněv as a researcher of Carpathian Rus' in the materials of his personal archive
původní článek
open access
vydavatelská verze
2024
,Dejiny
,2024
(1)
Statja osnovana na materialach, obnaružennych v 2022 g. v Gosudarstvennom regionalnom archive v Prage (SOA v Praze) i otnosjaščichsja k ličnomu archivu russkogo etnografa, istorika, archeologa i archivista-emigranta Vsevoloda ...
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Effects of 6 weeks of complex training on athletic performance and post-activation performance enhancement effect magnitude in soccer players: a cross-sectional randomized study
původní článek
open access
vydavatelská verze
2025
,Biology of Sport
,42
(1)
This study aimed to determine the effect of complex training (CT) on post-activation performance enhancement (PAPE) effect magnitude, 5- and 30-m linear sprint, 5-0-5 change of-direction (COD), back squat (BS) and hip ...
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The Linked Complexity of Coseismic and Postseismic Faulting Revealed by Seismo‐Geodetic Dynamic Inversion of the 2004 Parkfield Earthquake
původní článek
open access
vydavatelská verze
2024
,Journal of Geophysical Research: Solid Earth
,2024
(November)
Several regularly recurring moderate-size earthquakes motivated dense instrumentation of theParkfield section of the San Andreas fault (SAF), providing an invaluable near-fault observatory. We present aseismo-geodetic ...
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