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Poslední příspěvky
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Epidemiology and healthcare utilization in motor neuron disease in Czechia
původní článek
omezený přístup
vydavatelská verze
2025
,Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
,26
(5-6)
The demographic and epidemiological profile of motor neuron disease (MND) in Czechia remains unknown, highlighting a critical gap; this study aims to examine the epidemiology of MND using population-based data. We conducted ...
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Genome integration of human DNA oncoviruses
původní článek
open access
postprint
2025
,Journal of Virology
Tumors of infectious origin globally represent 13%. Oncogenic DNA viruses such as human papillomavirus (HPV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV) are responsible for approximately 60% of these tumors. ...
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Memantine Administration Enhances Glutamatergic and GABAergic Pathways in the Human Hippocampus of Alzheimer's Disease Patients
původní článek
open access
preprint
2025
,Proteomics
,Epub: 2025 Jul 25
(v tisku)
One of the traditional treatments in Alzheimer's disease (AD) is administration of memantine, the NMDA receptor antagonist. However, the molecular mechanism of the complex memantine action and the impact on the hippocampal ...
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Inhibition of Aspartate β-Hydroxylase Enhances Anti-Tumor Immunity
původní článek
open access
vydavatelská verze
2025
,ImmunoTargets and Therapy
,14
(July)
Aspartate β-hydroxylase (ASPH) contributes to carcinogenesis by promoting tumor cell proliferation, migration, and invasion. The enzymatic activity of ASPH can be inhibited by small molecule inhibitors that have been shown ...
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A post-COVID-19 upsurge in Group A Streptococcus in the Czech Republic was driven by emm1 and emm12 with shared virulence factors
původní článek
open access
vydavatelská verze
2025
,Journal of Infection and Public Health
,18
(10)
BACKGROUND: In 2023, a significant increase in Streptococcus pyogenes, Group A Streptococcus (GAS) culture positivity was observed in Czech microbiological laboratories. We conducted a multicentre study to obtain epidemiological ...
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Confinement as a key but overlooked factor controlling erosion rate in loess pipes and tunnels
původní článek
open access
vydavatelská verze
2025
,Geomorphology
,486
(October)
Approximately 10 % of the Earth's land surface is covered by loess. The ability of loess to maintain vertical cliffs indicates its considerable strength, but at the same time loess is susceptible to rapid erosion. The ...
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Native and decellularized porcine vena cava: Histological analysis and in vitro repopulation
původní článek
open access
vydavatelská verze
2025
,Biomaterials Advances
,177
(December)
Current standards in vascular reconstruction imply the use of autologous or synthetic material. Despite being standard, autologous grafts are limited by pathologies already affecting the patient and possible complications ...
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Metodika analýzy, vykazování a komparace úrovně předčasné úmrtnosti
Methodology for analyzing, reporting, and comparing level of premature mortality
certifikovaná metodika
open access
vydavatelská verze
2025
Navržená metodika analýzy, vykazování a komparace úrovně předčasné úmrtnosti vychází z několika bodů klíčových potřeb, které by tato metodika měla splňovat: (1) mezinárodní, meziregionální a časovou srovnatelnost, (2) ...
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Arterial wall enhancement indicates higher reperfusion rates in non-ruptured aneurysms after endovascular treatment with stent-assisted coiling
původní článek
open access
preprint
2025
,Neuroradiology
Background and purpose: There are differing results in recent literature concerning aneurysmal wall enhancement (AWE) after endovascular treatment (ET) of intracranial aneurysms (IAs). The aim of this retrospective study ...
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Consistent summer temperature signals in a latewood blue intensity network from the upper tree line in the Caucasus
původní článek
open access
vydavatelská verze
2025
,Dendrochronologia
,92
(August)
Climate variability in the Caucasus region significantly influences tree growth in alpine tree line ecotones. However, long-standing human land-use history disrupted the natural equilibrium between montane forests and ...
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Hostile Environments: Modifying Surfaces to Block Microbial Adhesion and Biofilm Formation
přehledový článek
open access
vydavatelská verze
2025
,Biomolecules
,15
(6)
Since the first observations of biofilm formation by microorganisms on various surfaces more than 50 years ago, it has been shown that most "unicellular" microorganisms prefer to grow in multicellular communities that often ...
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Developing molecular surveillance of SARS-CoV-2 in the Czech Republic (2021-2022)
původní článek
open access
vydavatelská verze
2025
,Scientific Reports
,15
(1)
Molecular surveillance was widely used during the COVID-19 pandemic to detect rapidly emerging variants and monitor the transmission of SARS-CoV-2 within communities. In 2021, the Czech COVID-19 Genomics Consortium (COG-CZ) ...
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The relationship between food security, fruit and vegetable consumption, and health-related factors in the late COVID-19 pandemic in Czechia: a cross-sectional study
původní článek
open access
vydavatelská verze
2025
,BMC Public Health
,25
(2025)
Background: Food insecurity is one of the social determinants of health and affects dietary quality and well-being. This study aimed to examine the associations among food insecurity, sociodemographic and economic factors, ...
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Uncovering agnoprotein interactions with cellular membranes during BKPyV infection in reservoir cells
abstrakt v elektronické podobě
open access
postprint
2025
BK polyomavirus (BKPyV), a widespread human virus, causes asymptomatic infectionsthat persist indefinitely. In immunosuppressed patients, particularly kidney transplantrecipients, reactivated viral replication can lead to ...
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Rezkova věcnost a její techniky
Rezek’s “Matter-of-Factness” and Its Techniques
původní článek
open access
vydavatelská verze
2025
,Filosofický časopis
,73
(2)
Esej rekonstruuje pojem věcnosti ve filosofii Petra Rezka a její zakotvení v imanenci naší zkušenosti, resp. v napětí, které vyvolávají dva požadavky na ni vázané: (1) podmíněnost věci tím, jak se jeví, a (2) současná ...
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Fosfomycin-resistant Escherichia coli: a FosA10 case in Italy
původní článek
open access
vydavatelská verze
2025
,JAC-Antimicrobial Resistance
,7
(2)
BACKGROUND: FosA10-producing Enterobacterales have an extremely low incidence in Europe. PATIENTS AND METHODS: In March 2024, an 83-year-old woman, hospitalized in the Modena Province, developed an infection with ...
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Too much of everything is bad: The case of Czech university students' work-study balance during the Covid-19 pandemic
původní článek
open access
vydavatelská verze
2025
,Journal on Efficiency and Responsibility in Education and Science
,18
(2)
Students are an exceptionally vulnerable population in comparison to any other age group. Manystudents face considerable stress stemming from the combined demands of their studies and, for some,the necessity to work. This ...
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Survey Experiments in Public Policy: A Systematic Literature Review
původní článek
open access
postprint
2025
,Review of Policy Research
This systematic literature review examines population-based survey experiments (PBSE) in public policy, analyzing 36 peer-reviewed articles from Web of Science and Scopus databases. Based on PBSE methodological literature ...
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On “Westsplaining,” Realism, and Technologies of the Self: A Foucauldian Reading of the Realist Commentary on Ukraine
původní článek
open access
vydavatelská verze
2024
,Journal of Regional Security
,19
(1)
The article offers a Foucauldian reading of the Western realist commentary on the Russo-Ukrainian war which often faces the charges of "Westsplaining." It situates this commentary in the broader context of knowledge ...
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Vývoj plodnosti v Česku v období pandemie covid-19: Mezinárodní srovnání a dosavadní poznatky
Fertility development in Czechia during the covid-19 pandemic: international comparision and current knowledge
přehledový článek
open access
vydavatelská verze
2025
,Demografie
,67
(1)
Tato studie zkoumá vývoj plodnosti v Česku v posledních třech desetiletích se zaměřením na dopad pandemie COVID-19. Na základě publikovaných zjištění z celé Evropy zkoumá, jak pandemie a související faktory, včetně očkovací ...
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