Lékařská fakulta v Plzni
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Poslední příspěvky
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The presence of multiple variants of IncF plasmid alleles in a single genome sequence can hinder accurate replicon sequence typing using in silico pMLST tools
původní článek
open access
postprint
2025
,mSystems
IncF plasmids are mobile genetic elements found in bacteria from the Enterobacteriaceae family and often carry critical antibiotic and virulence gene cargo. The classification of IncF plasmids using the plasmid Multi-Locus ...
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Phenotypic and genotypic characterization of Candida parapsilosis complex isolates from a Lebanese hospital
původní článek
open access
postprint
2025
,Scientific Reports
,15
(1)
The opportunistic pathogen Candida parapsilosis is a major causative agent of candidiasis leading to death in immunocompromised individuals. Azoles are the first line of defense in their treatment. The purpose of this study ...
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Epigenetic Characterization of Squamous Cell Carcinoma and Mucoepidermoid Carcinoma Based on DNA Methylation Data: An In-Silico Study
abstrakt v časopisu
open access
vydavatelská verze
2025
,Oxford
,Elsevier Ltd.
,EJC Skin Cancer
,3
(S1)
Background: A recent study demonstrated that parotid squamous cell carcinomas (SCCs) are most potentially metastatic cutaneous SCCs. To define whether epigenetic alterations may explain the different molecular events between ...
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Letter to the Editor: Isolation of Carbapenemase-Producing Pseudomonas aeruginosa from a Waste-Water Sample Collected from a Greek University Hospital
letter to the editors
open access
postprint
2025
,Microbial Drug Resistance
,31
(3)
The spread of carbapenemase-producing bacteria into clinical settings has dramatically worsen the public health situation. But, also, the isolation of such organisms from samples of environmental and wildlife origin has ...
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Visual presentation of age differences in relative survival of hematological neoplasms in Sweden and the neighboring countries
původní článek
open access
vydavatelská verze
2025
,Annals of Hematology
,104
(3)
For many hematological malignancies (HMs) survival among older patients is compromised. We want to test the most up-to-date age-group-specific survival differences in five hematological malignancies, Hodgkin lymphoma (HL), ...
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Genomic analysis of extended-spectrum beta-lactamase-producing E. coli from Czech diary calves and their caretakers
původní článek
open access
postprint
2025
,Frontiers in Veterinary Science
,12
(March)
INTRODUCTION: The increasing prevalence of antimicrobial resistance in livestock, particularly the dissemination of extended-spectrum beta-lactamase-producing Escherichia coli, poses a significant zoonotic and public health ...
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Lurcher Mouse as a Model of Cerebellar Syndromes
přehledový článek
open access
vydavatelská verze
2025
,The Cerebellum
,24
(2)
Cerebellar extinction lesions can manifest themselves with cerebellar motor and cerebellar cognitive affective syndromes. For investigation of the functions of the cerebellum and the pathogenesis of cerebellar diseases, ...
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Anatomical biliary reconstruction as an ultimum refugium for selective cases-History and current state of knowledge
přehledový článek
open access
vydavatelská verze
2024
,Journal of Hepato-Biliary-Pancreatic Sciences
,31
(11)
Reconstruction of extrahepatic bile ducts is a staple procedure of HPB surgery. The current standard for most cases is a nonanatomical bilioenteric reconstruction, a satisfactory option for the majority of patients. However, ...
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EPIDEMIOLOGY OF CARB APENEMASE PRODUCING ENTEROBACTERALES IN THE CZECH REPUBLIC
abstrakt v konferenčním sborníku
open access
vydavatelská verze
2024
,NIVB Meeting - Book of abstracts
Carbapenemases are versatile β-lactamases capable of hydrolyzing carbapenem antibiotics. They are classified into Ambler classes A, B, and D. Class A carbapenemases, such as Klebsiella pneumoniaecarbapenemase (KPC) ...
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In vivo evaluation of selenium-tellurium based nanoparticles as a novel treatment for bovine mastitis
původní článek
open access
vydavatelská verze
2024
,Journal of Animal Science and Biotechnology
,15
(1)
Background Bovine mastitis is one of the main causes of reduced production in dairy cows. The infection of the mammary gland is mainly caused by the bacterium Staphylococcus aureus, whose resistant strains make the treatment ...
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Multidrug-resistant ESBL-producing Klebsiella pneumoniae complex in Czech hospitals, wastewaters and surface waters
původní článek
open access
postprint
2024
,Antimicrobial Resistance and Infection Control
,13
(1)
BACKGROUND: Multidrug-resistant (MDR) bacteria pose a significant challenge to the treatment of infectious diseases. Of particular concern are members of the Klebsiella pneumoniae species complex (KpSC), which are frequently ...
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Changing dynamics of antibiotic resistant Escherichia in Caspian gulls shows the importance of longitudinal environmental studies
původní článek
embargo
postprint
2024
,Environment International
,186
(April)
This study is focused on Escherichia spp. isolates resistant to critically important antibiotics (cefotaxime, ciprofloxacin and colistin) among Caspian gull's (Larus cachinnans) chicks nesting in the Nove Mlyny Water ...
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Antibiotic-resistant Escherichia coli from treated municipal wastewaters and Black-headed Gull nestlings on the recipient river
původní článek
embargo
postprint
2024
,One Health
,19
(December)
Wastewaters belong among the most important sources of environmental pollution, including antibiotic-resistant bacteria. The aim of the study was to evaluate treated wastewaters as a possible transmission pathway for ...
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The faecal microbiome of the Australian silver gull contains phylogenetically diverse ExPEC, aEPEC and Escherichia coli carrying the transmissible locus of stress tolerance
původní článek
embargo
postprint
2024
,Science of the Total Environment
,919
(April)
Wildlife are implicated in the dissemination of antimicrobial resistance, but their roles as hosts for Escherichia coli that pose a threat to human and animal health is limited. Gulls (family Laridae) in particular, are ...
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Survival in Thyroid Cancer in Sweden From 1999 To 2018
původní článek
open access
vydavatelská verze
2024
,Clinical Epidemiology
,16
(2 October 2024)
INTRODUCTION: Thyroid cancer (TC) is diagnosed in several histological types which differ in their clinical characteristics and survival. We aim to describe how they influence TC survival in Sweden. METHODS: Cancer data ...
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Complex Relationships between Diagnostics and Survival in Chronic Lymphocytic Leukemia in Denmark, Finland, Norway, and Sweden
původní článek
open access
vydavatelská verze
2024
,Cancers
,16
(18)
BACKGROUND: Chronic lymphocytic leukemia (CLL) is a common hematological malignancy with highly variable clinical presentation. Many patients never require any treatment but for the others, chemotherapy, immunochemotherapy, ...
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A novel F type plasmid encoding mcr-10 in a clinical Enterobacter ludwigii strain from a tertiary hospital in Czech Republic
původní článek
open access
vydavatelská verze
2024
,Journal of Global Antimicrobial Resistance
,37
(June)
Objective: Here we describe a novel IncFIA plasmid harboring mcr-10 gene in a clinical Enterobacter ludwigii strain isolated at the University Hospital in Pilsen in the Czech Republic.Methods: The strain was subjected to ...
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Percutaneous transthoracic needle biopsy of lung lesions is a safe method associated with a very low risk of pleural recurrence
původní článek
open access
vydavatelská verze
2025
,Biomedical Papers
,169
(1)
AIM: Percutaneous transthoracic needle biopsy (PTNB), an alternative to bronchoscopic confirmation of lung lesions, is today being associated with a risk of pneumothorax and hemorrhage. Further, there are no data on the ...
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Emergence of Escherichia coli ST131 carrying carbapenemase genes, European Union/European Economic Area, August 2012 to May 2024
původní článek
open access
postprint
2024
,Eurosurveillance
,29
(47)
Analysis of 594 isolates of Escherichia coli sequence type (ST)131 and its single locus variants carrying carbapenemase genes from 17 European Union/European Economic Area countries revealed acquisition of 18 carbapenemase ...
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Co-introduction into a delicate island ecosystem: metastrongyloid nematodes (superfamily Metastrongyloidea) of veterinary and medical importance circulating in aquatic and terrestrial environments of Tenerife (Canary Islands)
původní článek
open access
postprint
2024
,Parasitology Research
,123
(10)
Metastrongyloid nematodes typically reside as adults in the cardiopulmonary systems of their mammalian definitive hosts, potentially causing severe diseases. Of particular concern are Angiostrongylus cantonensis and A. ...
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