Repozitář publikační činnosti UK: Poslední příspěvky

Zobrazují se záznamy 441-460 z 1467

    • Investigation of BKPyV life cycle, activation of innate immune responses and membrane remodeling in microvascular endothelial cells 

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      Bruštíková, Kateřina

      ;

      Rjabčenko, Boris

      ;

      Liebl, David

      ;

      Horníková, Lenka

      ;

      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Polyomaviruses (PyVs) are small double-stranded DNA viruses that occur widely in nature. Among the 14 known human PyVs, three are particularly relevant: BK Polyomavirus (BKPyV), JC polyomavirus, and Merkel cell carcinoma ...

    • Relationship between yeast virus like elements and poxviruses at the transcriptional level 

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      Vopálenský, Václav

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      Sýkora, Michal

      ;

      Mělková, Zora

      ;

      Barvík, Ivan

      ;

      Mašek, Tomáš

      ;

      Horáčková, Kamila

      ;

      Pospíšek, Martin

      2024

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Yeast cytoplasmic double-stranded DNA virus-like elements (VLEs, also known as linear plasmids) were found in a number of yeast species belonging to nine genera. The Kluyveromyces lactis pGKL1/2 plasmids, which serve as ...

    • Interactome analysis of the mouse polyomavirus large T antigen 

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      Štaflová, Karolína

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      Šroller, Vojtěch

      ;

      Pichová, Iva

      ;

      Bártová, Jana

      ;

      Rjabčenko, Boris

      ;

      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2024

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Polyomaviruses are small nonenveloped viruses that replicate in the nucleus of the host cell. The mouse polyomavirus (MPyV) large T antigen (LT) is the multifunctional protein expressed in the early phase of the viral ...

    • Small-molecule activators of NRF1 transcriptional activity prevent protein aggregaton 

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      Sedláček, Jindřich

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      Šmahelová, Zuzana

      ;

      Adámek, Michael

      ;

      Šubová, Dominika

      ;

      Majer, Pavel

      ;

      Svobodová, Lucie

      ;

      Kadlecová, Alena

      ;

      Petrezsélyová, Silvia

      ;

      Machara, Aleš

      ;

      Grantz Šašková, Klára

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Intracellular protein aggregation causes proteotoxic stress, underlying highly debilitating neurodegenerative disorders in parallel with decreased proteasome activity.Nevertheless, under such stress conditions, the expression ...

    • Novel autophagy inducer inhibits hepatitis B virus S antigen secretion 

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      Šmahelová, Zuzana

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      Pimková Polidarová, Markéta

      ;

      Sedláček, Jindřich

      ;

      Berehovska, Olena

      ;

      Janovec, Václav

      ;

      Adámek, Michael

      ;

      Hirsch, Ivan

      ;

      Machara, Aleš

      ;

      Grantz Šašková, Klára

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Chronic hepatitis B (CHB), a liver infection caused by the hepatitis B virus (HBV), affects more than 300 million people worldwide. If left untreated, CHB can progress to liver cirrhosis and hepatocellular carcinoma, ...

    • Parental views on their children’s smartphone use during personal and relational activities 

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      vydavatelská verze

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      Lukavská, Kateřina

      ;

      Gabrhelík, Roman

      2024

      ,

      PLoS One

      ,

      19

      (8)

      Given the negative outcomes associated with smartphone use during personal and relational activities (SUPRA), parents strive to regulate its use among their children. However, media parenting recommendations lack knowledge ...

    • DDI2 protease controls embryonic development and inflammation via TCF11/NRF1 

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      Nedomová, Monika

      ;

      Haberecht-Müller, Stefanie

      ;

      Möller, Sophie

      ;

      Venz, Simone

      ;

      Procházková, Michaela

      ;

      Procházka, Jan

      ;

      Sedlák, František

      ;

      Chawengsaksophak, Kallayanee

      ;

      Hammer, Elke

      ;

      Kašpárek, Petr

      ;

      Adámek, Michael

      ;

      Sedláček, Radislav

      ;

      Konvalinka, Jan

      ;

      Elke, Kruger

      ;

      Grantz Šašková, Klára

      2024

      ,

      iScience

      ,

      27

      (10)

      DDI2 is an aspartic protease that cleaves polyubiquitinated substrates. Upon proteotoxic stress, DDI2 activates the transcription factor TCF11/NRF1 (NFE2L1), crucial for maintaining proteostasis in mammalian cells, enabling ...

    • Positive Effect of a Cooling Cap on Functional Performance in Thermosensitive People with Multiple Sclerosis: A Randomized Controlled Trial 

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      Novotná, Klára

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      Dedinova, K.

      ;

      Meňkyová, Ingrid

      ;

      Uher, Tomáš

      ;

      Kubala Havrdová, Eva

      ;

      Angerová, Yvona

      2024

      ,

      Acta Neurologica Scandinavica

      ,

      2024

      (April)

      Background. Up to 80% of people with MS experience worsening of their condition upon an increase in body temperature. Therefore, various options of cooling are being evaluated to help improve physical performance in people ...

    • School choice and parenting strategies among Czech middle‐class parents : Implications for social segregation in public schools 

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      Smith Slámová, Radka

      ;

      Simonová, Jaroslava

      2024

      ,

      Sociology Compass

      ,

      e13248

      (23.7.2024)

      Research examining middle-class parents' school choices often overlooks parents in post-socialist nations, where social reproduction may occur differently than in Western urban contexts. To bridge this gap, our study ...

    • Why do teachers leave schools? Evidence from lower secondary schools in the Czech Republic 

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      vydavatelská verze

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      Straková, Jana

      ;

      Simonová, Jaroslava

      2024

      ,

      International Journal of Educational Management

      ,

      neuveden

      (18.2.2024)

      Purpose - This study aims to supplement the international knowledge on factors determining retention in theteaching profession with findings from the Czech Republic. The study aims to answer the question of whatfactors on ...

    • Proteogenomic Characterization of Pseudomonas veronii SM-20 Growing on Phenanthrene as Only Carbon and Energy Source 

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      Zavala Meneses, Sofia Guadalupe

      ;

      Firrincieli, Andrea

      ;

      Chalova, Petra

      ;

      Pajer, Petr

      ;

      Checcucci, Alice

      ;

      Škultéty, Ľudovít

      ;

      Cappelletti, Martina

      2024

      ,

      Microorganisms

      ,

      12

      (4)

      In this study, we conducted an extensive investigation of the biodegradation capabilities and stress response of the newly isolated strain Pseudomonas veronii SM-20 in order, to assess its potential for bioremediation of ...

    • More Than Meets the Reply: Examining Emotional Belonging in Far-Right Social Media Space 

      původní článek

      omezený přístup

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      Collins, Jonathan

      2024

      ,

      Social media + Society

      ,

      10

      (3)

      This article challenges prevailing assumptions that fringe social media platforms predominantly serve as unmoderated hate-filled spaces for far-right communication by examining the userbase's emotional connection to these ...

    • The effect of aspartate β-hydroxylase inhibition on cancer immunotherapy 

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      Johari, Shweta Dilip

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      Krausová, Kateřina

      ;

      Žucha, Barbora

      ;

      Madureira Trufen, Carlos Eduardo

      ;

      Poláková, Ingrid

      ;

      Olsen, Mark

      ;

      Šmahel, Michal

      2024

      ,

      Neuveden

      Aspartate β-hydroxylase (ASPH) is overexpressed in 70-90% of various solid tumors, contributing to tumor cell proliferation, migration, and invasion. In addition, recombinant ASPH inhibits natural killer (NK) cells, but ...

    • Self-administered mindfulness interventions reduce stress in a large, randomized controlled multi-site study 

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      Sparacio, Alessandro

      ;

      IJzerman, Hans

      ;

      Ropovik, Ivan

      ;

      Giorgini, Filippo

      ;

      Spiessens, Christoph

      ;

      Uchino, Bert N.

      ;

      Landvatter, Joshua

      ;

      Tacana, Tracey

      ;

      Diller, Sandra J.

      ;

      Derrick, Jaye L.

      ;

      Segundo, Joahana

      ;

      Pierce, Jace D.

      ;

      Ross, Robert M.

      ;

      Francis, Zoë

      ;

      LaBoucane, Amanda

      ;

      Ma-Kellams, Christine

      ;

      Ford, Maire B.

      ;

      Schmidt, Kathleen

      ;

      Wong, Celia C.

      ;

      Higgins, Wendy C.

      ;

      Stone, Bryant M.

      ;

      Stanley, Samantha K.

      ;

      Ribeiro, Gianni

      ;

      Fuglestad, Paul T.

      ;

      Jaklin, Valerie

      ;

      Kübler, Andrea

      ;

      Ziebell, Philipp

      ;

      Jewell, Crystal L.

      ;

      Kovas, Yulia

      ;

      Allahghadri, Mahnoosh

      ;

      Fransham, Charlotte

      ;

      Baranski, Michael F.

      ;

      Burgess, Hannah

      ;

      Benz, Annika B.E.

      ;

      DeSousa, Maysa

      ;

      Nylin, Catherine E.

      ;

      Brooks, Janae C.

      ;

      Goldsmith, Caitlyn M.

      ;

      Benson, Jessica M.

      ;

      Griffin, Siobhán M.

      ;

      Dunne, Stephen

      ;

      Davis, William E.

      ;

      Watermeyer, Tam J.

      ;

      Meese, William B.

      ;

      Howell, Jennifer L.

      ;

      Standiford Reyes, Laurel

      ;

      Strickland, Megan G.

      ;

      Dickerson, Sally S.

      ;

      Pescatore, Samantha

      ;

      Skakoon-Sparling, Shayna

      ;

      Wunder, Zachary I.

      ;

      Day, Martin V.

      ;

      Brenton, Shawna

      ;

      Linden, Audrey H.

      ;

      Hawk, Christopher E.

      ;

      O’Brien, Léan V.

      ;

      Urgyen, Tenzin

      ;

      McDonald, Jennifer S.

      ;

      van der Schans, Kim Lien

      ;

      Blocker, Heidi

      ;

      Ng Tseung-Wong, Caroline

      ;

      Jiga-Boy, Gabriela M.

      2024

      ,

      Nature Human Behaviour

      ,

      8

      (11.6.2024)

      Mindfulness witnessed a substantial popularity surge in the past decade, especially as digitally self-administered interventions became available at relatively low costs. Yet, it is uncertain whether they effectively help ...

    • Defects in B-lymphopoiesis and B-cell maturation underlie prolonged B-cell depletion in ANCA-associated vasculitis 

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      Thiel, Jens

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      Schmidt, Franziska M

      ;

      Lorenzetti, Raquel

      ;

      Troilo, Arianna

      ;

      Janowska, Iga

      ;

      Nießen, Lena

      ;

      Pfeiffer, Sophie

      ;

      Staniek, Julian

      ;

      Benassini, Bruno

      ;

      Bott, Marei-Theresa

      ;

      Korzhenevich, Jakov

      ;

      Konstantinidis, Lukas

      ;

      Burgbacher, Frank

      ;

      Dufner, Ann-Katrin

      ;

      Frede, Natalie

      ;

      Voll, Reinhard E

      ;

      Stuchlý, Jan

      ;

      Bakardjieva, Marina

      ;

      Kalina, Tomáš

      ;

      Smulski, Cristian Roberto

      ;

      Venhoff, Nils

      ;

      Rizzi, Marta

      2024

      ,

      Annals of the Rheumatic Diseases

      ,

      83

      (11)

      OBJECTIVES: B-cell depletion time after rituximab (RTX) treatment is prolonged in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) compared with other autoimmune diseases. We investigated central and ...

    • Tviblindi algorithm identifies branching developmental trajectories of human B-cell development and describes abnormalities in RAG-1 and WAS patients 

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      Bakardjieva, Marina

      ;

      Pelák, Ondřej

      ;

      Wentink, Marjolein

      ;

      Glier, Hana

      ;

      Novák, David

      ;

      Stančíková, Jitka

      ;

      Kužílková, Daniela

      ;

      Mejstříková, Ester

      ;

      Janowska, Iga

      ;

      Rizzi, Marta

      ;

      van der Burg, Mirjam

      ;

      Stuchlý, Jan

      ;

      Kalina, Tomáš

      2024

      ,

      European Journal of Immunology

      ,

      54

      (12)

      Detailed knowledge of human B-cell development is crucial for the proper interpretation of inborn errors of immunity and malignant diseases. It is of interest to understand the kinetics of protein expression changes during ...

    • Giant Cell Temporal Arteritis Followed by Severe Encephalopathy Induced by Immunotherapy in a Patient with Metastatic Renal Cell Carcinoma Achieving Durable Partial Response: A Case Report 

      kazuistika

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      Fiala, Ondřej

      ;

      Tkadlecová, Michaela

      ;

      Pivovarčíková, Kristýna

      ;

      Baxa, Jan

      ;

      Stránský, Petr

      ;

      Šiková, Dominika

      ;

      Hora, Milan

      ;

      Fínek, Jindřich

      2024

      ,

      Case Reports in Oncology

      ,

      17

      (1)

      Introduction: Combined immuno-oncology (IO) regimens are the cornerstone of the current front-line systemic therapy for metastatic renal cell carcinoma (mRCC). Despite the fact that combined IO regimens show high efficacy, ...

    • Steady survival improvements in soft tissue and bone sarcoma in the Nordic countries through 50 years 

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      Tichánek, Filip

      ;

      Försti, Asta

      ;

      Hemminki, Otto

      ;

      Hemminki, Akseli

      ;

      Hemminki, Kari Jussi

      2024

      ,

      Cancer Epidemiology

      ,

      29

      (October)

      Purpose: Sarcomas are rare cancers with many subtypes in soft tissues, bone and cartilage. International survival trends in these cancers are not well known. We present 50-year survival trends for soft tissue sarcoma (STS) ...

    • Adenotonsillar pathology in mucopolysaccharidoses - lysosomal storage predominates in paracortical CD63+ cells 

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      Murgašová, Lenka

      ;

      Hůlková, Helena

      ;

      Barešová, Veronika

      ;

      Jurovčík, Michal

      ;

      Stříteský, Jan

      ;

      Jurickova, Katarina

      ;

      Magner, Martin

      ;

      Sikora, Jakub

      2024

      ,

      Virchows Archiv

      ,

      484

      (1)

      Despite the adenoids are regularly removed in patients with mucopolysaccharidoses (MPS), the underlying tissue and cellular pathologies remain understudied. We characterized an (immuno)histopathologic and ultrastructural ...

    • A Fast HPLC/UV Method for Determination of Ketoprofen in Cellular Media 

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      Vozniuk, Oleksandra

      ;

      Kejík, Zdeněk

      ;

      Veselá, Kateřina

      ;

      Skaličková, Markéta

      ;

      Novotný, Petr

      ;

      Hromádka, Róbert

      ;

      Hajduch, Jan

      ;

      Martásek, Pavel

      ;

      Jakubek, Milan

      2024

      ,

      ChemistryOpen

      ,

      13

      (3)

      A simple, sensitive and quick HPLC method was developed for the determination of ketoprofen in cell culture media (EMEM, DMEM, RPMI). Separation was performed using a gradient on the C18 column with a mobile phase of ...