Repozitář publikační činnosti UK: Poslední příspěvky
Zobrazují se záznamy 421-440 z 1467
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Learnability of state spaces of physical systems is undecidable
původní článek
embargo
vydavatelská verze
2024
,Journal of Computational Science
,83
(December 2024)
Despite an increasing role of machine learning in science, there is a lack of results on limits of empirical exploration aided by machine learning. In this paper, we construct one such limit by proving undecidability of ...
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Secukinumab Causing Medication-Related Osteonecrosis of the Jaw, in a Patient Diagnosed with Psoriasis and Rheumatoid Arthritis
kazuistika
open access
vydavatelská verze
2024
,Psoriasis
,14
(23 September 2024)
The use of antiangiogenic and antiresorptive medications, particularly in patients with cancer or osteoporosis, can lead to osteonecrosis of the jaw following tooth extraction, trauma or arising spontaneously- A condition ...
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Genetic And Environmental Associations Of Nonspecific Chromosomal Aberrations
přehledový článek
omezený přístup
vydavatelská verze
2024
,Mutagenesis
Nonspecific structural chromosomal aberrations (CAs) are found in around 1% of circulating lymphocytes from healthy individuals but the frequency may be higher after exposure to carcinogenic chemicals or radiation. CAs ...
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Social Mobility of Elites in East-Central Europe in Historical Perspective
kapitola v kolektivní monografii
open access
vydavatelská verze
2024
,Oldenbourg
,Walter de Gruyter GmbH
,Climbing up the Social Ladder? Social Mobility of Elites in East-Central Europe in the Long 19th Century
The chapter discusses the concept of the social mobility and illustrates how historians of modern-time elites in Central and Eastern Europe coneptualize and approach social mobility in conjunction with the more conventional ...
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Climbing up the Social Ladder? Social Mobility of Elites in East-Central Europe in the Long 19th Century
monografie
open access
vydavatelská verze
2024
,Oldenbourg
,Walter de Gruyter GmbH
Social mobility is about climbing the societal ladder, or switching to a better, more promising or rewarding position. But how does this work for those already atop or very close to it? The studies in the book explore ...
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Medium-run effects of COVID-19 induced distant learning on students’ academic performance
původní článek
open access
vydavatelská verze
2024
,Labour Economics
,Neuveden
(89)
Administrative data on bachelor students for 2014/15 to 2022/23 academic years are used to analyze their performance before, during, and - what is new in the literature - after the COVID-19 pandemic. The analysis reveals ...
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COVID angels fighting daily demons? Mental well-being of healthcare workers and religiosity
původní článek
open access
vydavatelská verze
2024
,European Economic Review
,162
(February 2024)
Relying on a unique survey of more than 15,000 healthcare workers conducted from June to August 2020 in Italy, we show that religious priming caused participants to have a less dramatic recollection of their distressful ...
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Enhancing the Antimycobacterial Efficacy of Pyridine-4-Carbohydrazide: Linkage to Additional Antimicrobial Agents via Oxocarboxylic Acids
původní článek
open access
postprint
2025
,RSC Medicinal Chemistry
,16
(February)
This study evaluates the antimycobacterial potential of novel "mutual" bioactive amides, combining pyridine-4-carbohydrazide (isoniazid, INH) with various antimicrobial agents (sulphonamides, 4-aminosalicylic acid, ...
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Metabolic dysfunction-associated steatotic liver disease-induced changes in the antioxidant system: a review
přehledový článek
open access
vydavatelská verze
2025
,Archives of Toxicology
,99
(January)
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a heterogeneous condition characterized by liver steatosis, inflammation, consequent fibrosis, and cirrhosis. Chronic impairment of lipid metabolism is ...
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Uncovering Relationships using Bayesian Networks: A Case Study on Conspiracy Theories
příspěvek v recenzovaném konferenčním sborníku
open access
vydavatelská verze
2024
,Nijmegen
,Proceedings of Machine Learning Research
,Probabilistic Graphical Models
,246
Bayesian networks (BNs) represent a probabilistic model that can visualize relationships between variables. We apply various BN structure learning algorithms to a large dataset from a Czech university entrance exam. This ...
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Monocyte cell death induced by sting agonists combines apoptosis, pyroptosis and caspase 8 activation
abstrakt v elektronické podobě
open access
postprint
2024
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,22
(6)
The cyclic GMP GMP-AMP synthase - stimulator of interferon genes (cGAS cGAS-STING) pathway recognizes double double-stranded DNA in cytoplasm. Activation of the pathway induces secretion of proinflammatory cytokines and ...
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Do kindergartens mitigate or exacerbate socioeconomic inequalities in language exposure? The case of home-based and kindergarten-based shared book reading activities in China
původní článek
open access
vydavatelská verze
2024
,Humanities & social sciences communications
,11
(1)
Shared book reading is a well-established practice for boosting children's language exposure and enhancing early development at home and in child care settings. The present study examined the socioeconomic gaps in home-based ...
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FosA3 emerging in clinical carbapenemase-producing C. freundii
původní článek
open access
vydavatelská verze
2024
,Frontiers in Cellular and Infection Microbiology
,14
(06 August 2024)
Fosfomycin (FOS) is an effective antibiotic against multidrug-resistant Enterobacterales, but its effectiveness is reducing. Little is known on the current prevalence of FosA enzymes in low-risk pathogens, such as Citrobacter ...
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Hidden potential of hydrazinecarboxamides (semicarbazides) as potential antimicrobial agents: A review
přehledový článek
open access
vydavatelská verze
2024
,Biomedicine & Pharmacotherapy
,180
(November)
Hydrazinecarboxamides (semicarbazides) are increasingly recognized as a versatile scaffold in developing potential antimicrobial agents. In addition to a brief overview of the synthetic methods to prepare them, this review ...
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ASPH inhibition reveals differential gene expression patterns in HPV-positive and HPV-negative cell lines
abstrakt v elektronické podobě
open access
postprint
2024
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,22
(6)
Cancer is associated with alterations in key cellular pathways, including the aspartate ββ-hydroxylase (ASPH) pathway, an oncogene upregulated in various carcinomas that plays a crucial role in tumor progression and ...
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The biomolecular markers for the personalized prediction of the treatment effect in patients with head and neck cancer: Pilot study
abstrakt v elektronické podobě
open access
postprint
2024
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,22
(6)
The clinical utility of liquid biopsies as diagnostic, predictive and prognostic biomarkers has been shown for several cancers. Our study analyses the dynamics of human papillomavirus (HPV) cell cell-free DNA (cfDNA) levels ...
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Unveiling viral diversity through wholevirome sequencing
abstrakt v elektronické podobě
open access
postprint
2024
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,22
(6)
In the dynamic landscape of viral metagenomics, our research focuses on whole-virome sequencing using the Novel enrichment technique of viromes protocol (NetoVir protocol, 1), which we have adapted to diverse starting ...
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Effect of the ADAR1 signalling pathway on HCV replication
abstrakt v elektronické podobě
open access
postprint
2024
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,22
(6)
The hepatitis C virus (HCV) is a member of the Flaviviridae family, the genome of which consists of a +RNA molecule. It causes hepatitis C, which infects tens of millions of people worldwide. Although new direct direct-acting ...
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Understanding the interplay between BK polyomavirus and celular restriction factors
abstrakt v elektronické podobě
open access
postprint
2024
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,22
(6)
The most important human polyomavirus are the Merkel cell polyomavirus, the etiological agent of 80% of Merkel cell carcinoma, JCPyV that causes progressive multifocal leukoencephalopathy and BKPyV which causes nephropathy. ...
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miRNA146a is a key component of immunnosupressive environment of hepatocytes chronically infected with HBV
abstrakt v elektronické podobě
open access
postprint
2024
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,22
(6)
Hepatitis B virus (HBV) causes acute hepatitis and can lead to chronic liver inflammation, often resulting in hepatocellular carcinoma. Known as a stealth virus, virus," HBV can evade recognition by the immune system. ...
