dc.contributor.author | Cinek, Ondřej | |
dc.contributor.author | Slavenko, Matvei | |
dc.contributor.author | Pomahačová, Renata | |
dc.contributor.author | Venháčová, Petra | |
dc.contributor.author | Petruželková, Lenka | |
dc.contributor.author | Škvor, Jaroslav | |
dc.contributor.author | Neumann, David | |
dc.contributor.author | Konečná, Petra | |
dc.contributor.author | Vosáhlo, Jan | |
dc.contributor.author | Kocourková, Kamila | |
dc.contributor.author | Strnadel, Jiří | |
dc.contributor.author | Průhová, Štěpánka | |
dc.contributor.author | Šumník, Zdeněk | |
dc.date.accessioned | 2023-01-20T08:28:03Z | |
dc.date.available | 2023-01-20T08:28:03Z | |
dc.date.issued | 2022 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14178/1649 | |
dc.description.abstract | OBJECTIVE: To explore type 1 diabetes incidence patterns during the pandemic years 2020 and 2021 in Czechia, to compare them to the trends from previous decade, and to test its association with indicators of containment measures and of pandemic severity (school closing and the all-cause excess mortality). RESEARCH DESIGN AND METODS: The Czech Childhood Diabetes Register is a population-based incidence register recording patients age 0-14.99 years at diabetes onset. Type 1 diabetes incidence in the pandemic period (April 2020 - end of observation Dec 2021) was compared by Poisson regression models to the incidence patterns over the past decade 2010-2019. RESULTS: During the pandemic years 2020-2021, 956 children 0-14.99 years old manifested with type 1 diabetes in Czechia. The observed incidence (27.2/100,000/year) was significantly higher than what was expected from the trends over 2010-2019 (incidence rate ratio, IRR = 1.16, 95%CI 1.06-1.28, P = 0.0022). The incidence had a trough during the first lockdown (March - May 2020), then it rose above expected values with no usual summer decrease. The assessed pandemic indicators (school closing and all-cause excess mortality) were not associated with the incidence levels. CONCLUSIONS: The COVID-19 pandemic was associated with a notable upward inflection of the type 1 diabetes incidence curve; the early months of the first lockdown were however hallmarked by a significant dip in new diabetes diagnoses. Long-term observation will show whether the increased incidence originated only from accelerating an advanced preclinical Stage 2 to overt diabetes, or whether the pandemic triggered new cases of islet autoimmunity. | en |
dc.language.iso | en | |
dc.relation.url | https://doi.org/10.1111/pedi.13405 | |
dc.rights | Creative Commons Uveďte původ-Neužívejte dílo komerčně 4.0 International | cs |
dc.rights | Creative Commons Attribution-NonCommercial 4.0 International | en |
dc.title | Type 1 diabetes incidence increased during the COVID-19 pandemic years 2020-2021 in Czechia: results from a large population-based paediatric register | en |
dcterms.accessRights | embargoedAccess | |
dcterms.license | https://creativecommons.org/licenses/by-nc/4.0/legalcode | |
dc.date.updated | 2023-10-02T06:13:57Z | |
dc.subject.keyword | COVID-19 | en |
dc.subject.keyword | incidence increase | en |
dc.subject.keyword | pandemic | en |
dc.subject.keyword | type 1 diabetes | en |
dc.relation.fundingReference | info:eu-repo/grantAgreement/UK/COOP/COOP | |
dc.relation.fundingReference | info:eu-repo/grantAgreement/FN/I-FN/I-FNM | |
dc.relation.fundingReference | info:eu-repo/grantAgreement/UK/I-UK/I-LFP | |
dc.relation.fundingReference | info:eu-repo/grantAgreement/FN/I-FN/I-FNP-42 | |
dc.relation.fundingReference | info:eu-repo/grantAgreement/FN/I-FN/I-FNHK | |
dc.relation.fundingReference | info:eu-repo/grantAgreement/MSM//LX22NPO5103 | |
dc.date.embargoStartDate | 2023-10-02 | |
dc.date.embargoEndDate | 2022-08-18 | |
dc.type.obd | 73 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | |
dc.identifier.doi | 10.1111/pedi.13405 | |
dc.identifier.utWos | 000849738500001 | |
dc.identifier.eidScopus | 2-s2.0-85137679347 | |
dc.identifier.obd | 613625 | |
dc.identifier.riv | RIV/00216208:11130/22:10445967 | |
dc.identifier.riv | RIV/00216208:11150/22:10445967 | |
dc.identifier.riv | RIV/00216208:11120/22:43923795 | |
dc.identifier.riv | RIV/00216208:11320/22:10445967 | |
dc.identifier.riv | RIV/00179906:_____/22:10445967 | |
dc.identifier.riv | RIV/00216208:11140/22:10445967 | |
dc.identifier.pubmed | 35982508 | |
dc.subject.rivPrimary | 30000::30200::30202 | |
dc.subject.rivSecondary | 30000::30200::30209 | |
dcterms.isPartOf.name | Pediatric Diabetes | |
dcterms.isPartOf.issn | 1399-543X | |
dcterms.isPartOf.journalYear | 2022 | |
dcterms.isPartOf.journalVolume | 23 | |
dcterms.isPartOf.journalIssue | 7 | |
uk.faculty.primaryId | 109 | |
uk.faculty.primaryName | 2. lékařská fakulta | cs |
uk.faculty.primaryName | Second Faculty of Medicine | en |
uk.faculty.secondaryId | 111 | |
uk.faculty.secondaryId | 51 | |
uk.faculty.secondaryId | 116 | |
uk.faculty.secondaryId | 110 | |
uk.faculty.secondaryId | 52 | |
uk.faculty.secondaryId | 112 | |
uk.faculty.secondaryName | Lékařská fakulta v Plzni | cs |
uk.faculty.secondaryName | Faculty of Medicine in Pilsen | en |
uk.faculty.secondaryName | Fakultní nemocnice Hradec Králové | cs |
uk.faculty.secondaryName | University Hospital Hradec Králové | en |
uk.faculty.secondaryName | Matematicko-fyzikální fakulta | cs |
uk.faculty.secondaryName | Faculty of Mathematics and Physics | en |
uk.faculty.secondaryName | 3. lékařská fakulta | cs |
uk.faculty.secondaryName | Third Faculty of Medicine | en |
uk.faculty.secondaryName | Fakultní nemocnice v Motole | cs |
uk.faculty.secondaryName | Motol University Hospital | en |
uk.faculty.secondaryName | Lékařská fakulta v Hradci Králové | cs |
uk.faculty.secondaryName | Faculty of Medicine in Hradec Kralove | en |
uk.department.primaryId | 109 | |
uk.department.primaryName | 2. lékařská fakulta | cs |
uk.department.primaryName | Second Faculty of Medicine | en |
uk.department.secondaryId | 1395 | |
uk.department.secondaryId | 100010693530 | |
uk.department.secondaryId | 696 | |
uk.department.secondaryId | 606 | |
uk.department.secondaryId | 1685 | |
uk.department.secondaryId | 5000000001 | |
uk.department.secondaryId | 1314 | |
uk.department.secondaryName | Dětská klinika | cs |
uk.department.secondaryName | Department of Paediatrics | en |
uk.department.secondaryName | Pediatrická klinika 2. LF UK a FN Motol | cs |
uk.department.secondaryName | Department of Paediatrics, 2nd Faculty of Medicine and Motol University Hospital | en |
uk.department.secondaryName | Dětská klinika | cs |
uk.department.secondaryName | Department of Pediatrics | en |
uk.department.secondaryName | Klinika dětí a dorostu 3. LF UK a FNKV | cs |
uk.department.secondaryName | Department of Children and Adolescents 3FM CU and UHKV | en |
uk.department.secondaryName | Pediatrická klinika | cs |
uk.department.secondaryName | Pediatrická klinika | en |
uk.department.secondaryName | Dětská klinika | cs |
uk.department.secondaryName | Department of Pediatrics | en |
uk.department.secondaryName | Katedra pravděpodobnosti a matematické statistiky | cs |
uk.department.secondaryName | Department of Probability and Mathematical Statistics | en |
dc.description.pageRange | 956-960 | |
dc.type.obdHierarchyCs | ČLÁNEK V ČASOPISU::článek v časopisu::původní článek | cs |
dc.type.obdHierarchyEn | JOURNAL ARTICLE::journal article::original article | en |
dc.type.obdHierarchyCode | 73::152::206 | en |
uk.displayTitle | Type 1 diabetes incidence increased during the COVID-19 pandemic years 2020-2021 in Czechia: results from a large population-based paediatric register | en |