Zobrazují se záznamy 1-20 z 328

    • Confinement as a key but overlooked factor controlling erosion rate in loess pipes and tunnels 

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      Vojtíšek, Jan

      ;

      Bruthans, Jiří

      ;

      Weiss, Tomáš

      2025

      ,

      Geomorphology

      ,

      486

      (October)

      Approximately 10 % of the Earth's land surface is covered by loess. The ability of loess to maintain vertical cliffs indicates its considerable strength, but at the same time loess is susceptible to rapid erosion. The ...

    • Metodika analýzy, vykazování a komparace úrovně předčasné úmrtnosti 

      Methodology for analyzing, reporting, and comparing level of premature mortality

      certifikovaná metodika

      open access

      vydavatelská verze

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      Hulíková Tesárková, Klára

      ;

      Dzúrová, Dagmar

      ;

      Kulhánová, Ivana

      ;

      Lustigová, Michala

      2025

      Navržená metodika analýzy, vykazování a komparace úrovně předčasné úmrtnosti vychází z několika bodů klíčových potřeb, které by tato metodika měla splňovat: (1) mezinárodní, meziregionální a časovou srovnatelnost, (2) ...

    • Consistent summer temperature signals in a latewood blue intensity network from the upper tree line in the Caucasus 

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      Dhyani, Rupesh

      ;

      Martin-Benito, Dario

      ;

      Doğan, Mehmet

      ;

      Kvaratskhelia, Revaz

      ;

      Köse, Nesibe

      ;

      Güner, Hüseyin Tuncay

      ;

      Schneider, Lea

      2025

      ,

      Dendrochronologia

      ,

      92

      (August)

      Climate variability in the Caucasus region significantly influences tree growth in alpine tree line ecotones. However, long-standing human land-use history disrupted the natural equilibrium between montane forests and ...

    • Hostile Environments: Modifying Surfaces to Block Microbial Adhesion and Biofilm Formation 

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      vydavatelská verze

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      Wilkinson, Derek

      ;

      Váchová, Libuše

      ;

      Palková, Zdena

      2025

      ,

      Biomolecules

      ,

      15

      (6)

      Since the first observations of biofilm formation by microorganisms on various surfaces more than 50 years ago, it has been shown that most "unicellular" microorganisms prefer to grow in multicellular communities that often ...

    • Developing molecular surveillance of SARS-CoV-2 in the Czech Republic (2021-2022) 

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      Šúri, Timotej

      ;

      Pfeiferová, Lucie

      ;

      Bezdíček, Matěj

      ;

      Svatoň, Jan

      ;

      Hampl, Vladimír

      ;

      Berka, Karel

      ;

      Jiřincová, Helena

      ;

      Lengerová, Martina

      ;

      Kolísko, Martin

      ;

      Nagy, Alexander

      ;

      Tachezy, Ruth

      ;

      Kolář, Michal

      ;

      Pačes, Jan

      2025

      ,

      Scientific Reports

      ,

      15

      (1)

      Molecular surveillance was widely used during the COVID-19 pandemic to detect rapidly emerging variants and monitor the transmission of SARS-CoV-2 within communities. In 2021, the Czech COVID-19 Genomics Consortium (COG-CZ) ...

    • The relationship between food security, fruit and vegetable consumption, and health-related factors in the late COVID-19 pandemic in Czechia: a cross-sectional study 

      původní článek

      open access

      vydavatelská verze

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      Ohno, Maika

      ;

      Vávra, Jan

      ;

      Jehlička, Petr

      2025

      ,

      BMC Public Health

      ,

      25

      (2025)

      Background: Food insecurity is one of the social determinants of health and affects dietary quality and well-being. This study aimed to examine the associations among food insecurity, sociodemographic and economic factors, ...

    • Uncovering agnoprotein interactions with cellular membranes during BKPyV infection in reservoir cells 

      abstrakt v elektronické podobě

      open access

      postprint

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      Lovtsov, Alexey

      ;

      Huerfano Meneses, Sandra

      2025

      BK polyomavirus (BKPyV), a widespread human virus, causes asymptomatic infectionsthat persist indefinitely. In immunosuppressed patients, particularly kidney transplantrecipients, reactivated viral replication can lead to ...

    • Vývoj plodnosti v Česku v období pandemie covid-19: Mezinárodní srovnání a dosavadní poznatky 

      Fertility development in Czechia during the covid-19 pandemic: international comparision and current knowledge

      přehledový článek

      open access

      vydavatelská verze

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      Slabá, Jitka

      ;

      Šťastná, Anna

      2025

      ,

      Demografie

      ,

      67

      (1)

      Tato studie zkoumá vývoj plodnosti v Česku v posledních třech desetiletích se zaměřením na dopad pandemie COVID-19. Na základě publikovaných zjištění z celé Evropy zkoumá, jak pandemie a související faktory, včetně očkovací ...

    • Impact of proteostasis workload on sensitivity to proteasome inhibitors in multiple myeloma 

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      open access

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      Sedláček, Jindřich

      2025

      ,

      Clinical and Experimental Medicine

      ,

      25

      (May)

      Genomic alterations and enormous monoclonal immunoglobulin production cause multiple myeloma to heavily depend on proteostasis mechanisms, including protein folding and degradation. These findings support the use of ...

    • Coordinated implementation of a conventional PCR assay to detect all Ebola and Marburg virus species in a European laboratory network 

      původní článek

      open access

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      Heimscha, Kim C.

      ;

      Bleickera, Tobias

      ;

      Besta, Till Dominik

      ;

      Presserb, Lance D.

      ;

      Molenkampc, Richard

      ;

      Jääskeläinen, Anne J.

      ;

      Milewska, Alexandra

      ;

      Šmahelová, Jana

      ;

      Baronti, Cécile

      ;

      Pappa, Sofia

      ;

      Tabaini, Irena

      ;

      Cordeiroj, Rita

      ;

      Marsili, Giulia

      ;

      Huik, Kristi

      ;

      Pinho dos Reism, Vincius

      ;

      Barzon, Luisa

      ;

      Maes, Piet

      ;

      Drosten, Christian

      ;

      Corman, Victor Max

      2025

      ,

      Journal of Clinical Virology

      ,

      178

      (June)

      Background: Filoviruses, including Ebola and Marburg viruses, cause severe hemorrhagic fever in humans and primates. These viruses pose significant threats to public health, making rapid and sensitive detection critical ...

    • Contaminant bioaccessibility in abandoned mine tailings in Namibia changes along a climatic gradient 

      původní článek

      open access

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      Ettler, Vojtěch

      ;

      Křížová, Tereza

      ;

      Mihaljevič, Martin

      ;

      Drahota, Petr

      ;

      Racek, Martin

      ;

      Kříbek, Bohdan

      ;

      Vaněk, Aleš

      ;

      Penížek, Vít

      ;

      Zádorova, Tereza

      ;

      Sracek, Ondra

      ;

      Mapani, Ben

      2025

      ,

      Environmental Science Processes & Impacts

      ,

      27

      (4)

      Fine-grained dust from tailing storage facilities in abandoned sulfide-ore mining areas represents an important source of environmental contamination. Fine fractions (<48 mu m and <10 mu m) of tailings from three old ...

    • Susceptibility of diverse sand fly species to Toscana virus 

      původní článek

      open access

      vydavatelská verze

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      Jančářová, Magdaléna

      ;

      Polanská, Nikola

      ;

      Thiesson, Adrien

      ;

      Arnaud, Frédérick

      ;

      Stejskalová, Markéta

      ;

      Rehbergerová, Markéta

      ;

      Kohl, Alain

      ;

      Viginier, Barbara

      ;

      Volf, Petr

      ;

      Ratinier, Maxime

      2025

      ,

      PLoS Neglected Tropical Diseases

      ,

      19

      (5)

      Toscana virus (TOSV) is an emerging but neglected human pathogen currently circulating around the Mediterranean basin including North Africa. Human illness ranges from asymptomatic or mild flu-like syndromes to severe ...

    • Altitude shapes gut microbiome composition accounting for diet, thyroid hormone levels, and host genetics in a subterranean blind mole rat 

      původní článek

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      Solak, Halil Mert

      ;

      Kreisinger, Jakub

      ;

      Čížková, Dagmar

      ;

      Sezgin, Efe

      ;

      Schmiedová, Lucie

      ;

      Murtskhvaladze, Marine

      ;

      Henning, Yoshiyuki

      ;

      Çolak, Faruk

      ;

      Matur, Ferhat

      ;

      Yanchukov, Alexey

      2024

      ,

      Frontiers in Microbiology

      ,

      15

      (November)

      The animal gut microbiome acts as a crucial link between the host and its environment, playing a vital role in digestion, metabolism, physiology, and fitness. Using 16S rRNA metabarcoding, we investigated the effect of ...

    • The impact of buried historical copper slags on contemporary soil contamination 

      původní článek

      open access

      vydavatelská verze

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      Kupczak, Krzysztof

      ;

      Warchulski, Rafał

      ;

      Ettler, Vojtěch

      ;

      Mihaljevič, Martin

      2025

      ,

      Journal of Geochemical Exploration

      ,

      273

      (June)

      This study focuses on the impact of historical metallurgical slags on contemporary soil and soil pore water contamination, and potential phytoavailibility of metal(loid)s based on the example of the former smelter (16th-18th ...

    • Evaluation of various membranes for blood-feeding in nine sand fly species and artificial feeding challenges in Sergentomyia minuta 

      původní článek

      open access

      vydavatelská verze

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      Hošková, Anna

      ;

      Vojtková, Barbora

      ;

      Stejskalová, Markéta

      ;

      Polanská, Nikola

      ;

      Jančářová, Magdaléna

      ;

      da Costa, Lidiane Medeiros

      ;

      Sant'Anna, Mauricio Roberto Viana

      ;

      Volf, Petr

      ;

      Sádlová, Jovana

      2025

      ,

      Parasites & Vectors

      ,

      18

      (1)

      BackgroundWe evaluated various membranes for blood-feeding in nine sand fly species from different genera and subgenera. Most of these species are vectors of human-pathogenic Leishmania, whereas Sergentomyia minuta is a ...

    • Proof-of-concept MALDI-TOF-MS assay for the detection of Toxin B enzymatic activity in Clostridioides difficile infection 

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      postprint

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      Dvořák, Josef

      ;

      Fojtík, Lukáš

      ;

      Adámková, Lyubina

      ;

      Vlková, Kateřina

      ;

      Študentová, Vendula

      ;

      Chudějová, Kateřina

      ;

      Geigerová, Lenka

      ;

      Volny, Michael

      ;

      Novak, Petr

      ;

      Hrabák, Jaroslav

      ;

      Pompach, Petr

      2025

      ,

      Microbiology Spectrum

      Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometers have become an integral part of all modern clinical microbiology laboratories. They serve as the key tool for pathogen identification ...

    • Dietary influence and immune balance: Regulating CD4+IEL responses and MHCII in the gut 

      přehledový článek

      omezený přístup

      vydavatelská verze

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      Dobeš, Jan

      ;

      Brabec, Tomáš

      2025

      ,

      Mucosal Immunology

      ,

      18

      (1)

      Over the past decade, interest in CD4 positive intraepithelial lymphocytes (IELs) has been growing. This subset of long-overlooked helper T cell plays critical roles in intestinal homeostasis and in responses to intestinal ...

    • Activation of the 26S Proteasome to Reduce Proteotoxic Stress and Improve the Efficacy of PROTACs 

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      Sedláček, Jindřich

      2024

      ,

      ACS Pharmacology & Translational Science

      ,

      8

      (1)

      The 26S proteasome degrades the majority of cellular proteins and affects all aspects of cellular life. Therefore, the 26S proteasome abundance, proper assembly, and activity in different life contexts need to be precisely ...

    • Thermally-induced release of arsenic from minerals and phases relevant to polluted natural systems affected by wildfires 

      původní článek

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      Tuhý, Marek

      ;

      Ettler, Vojtěch

      ;

      Rohovec, Jan

      ;

      Stonová, Kateřina

      ;

      Matoušková, Šárka

      ;

      Drahota, Petr

      ;

      Sullivan, Andrew L.

      2025

      ,

      Applied Geochemistry

      ,

      182

      (March)

      Fire-induced arsenic (As) emission from contaminated biomass or soil is dependent on its solid-phase speciation. To quantify the nature of this release, environmentally relevant As-bearing compounds (sulfides, sulfosalts, ...

    • How to Measure Sustainable Housing: A Proposal for an Indicator-Based Assessment Tool 

      původní článek

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      Adamec, Jakub

      ;

      Janoušková, Svatava

      ;

      Hák, Tomáš

      2021

      ,

      Sustainability

      ,

      13

      (3)

      Housing drives urban development and has a significant potential for contributing to sustainability. However, ample sustainability indicator sets fail to include relevant indicators of sustainable housing-assessment seems ...