Repozitář publikační činnosti UK: Recent submissions
Now showing items 321-340 of 1468
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Changing dynamics of antibiotic resistant Escherichia in Caspian gulls shows the importance of longitudinal environmental studies
original article
embargoed access
accepted version
2024
,Environment International
,186
(April)
This study is focused on Escherichia spp. isolates resistant to critically important antibiotics (cefotaxime, ciprofloxacin and colistin) among Caspian gull's (Larus cachinnans) chicks nesting in the Nove Mlyny Water ...
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Antibiotic-resistant Escherichia coli from treated municipal wastewaters and Black-headed Gull nestlings on the recipient river
original article
embargoed access
accepted version
2024
,One Health
,19
(December)
Wastewaters belong among the most important sources of environmental pollution, including antibiotic-resistant bacteria. The aim of the study was to evaluate treated wastewaters as a possible transmission pathway for ...
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The faecal microbiome of the Australian silver gull contains phylogenetically diverse ExPEC, aEPEC and Escherichia coli carrying the transmissible locus of stress tolerance
original article
embargoed access
accepted version
2024
,Science of the Total Environment
,919
(April)
Wildlife are implicated in the dissemination of antimicrobial resistance, but their roles as hosts for Escherichia coli that pose a threat to human and animal health is limited. Gulls (family Laridae) in particular, are ...
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The use of patient-derived xenografts and patient-derived organoids in the search for new therapeutic regimens for pancreatic carcinoma. A review
summarizing article
open access
published version
2025
,Biomedicine & Pharmacotherapy
,182
(January)
Patient-derived organoids (PDOs) and xenografts (PDXs) are powerful tools for personalized medicine in pancreatic cancer (PC) research. This study explores the complementary strengths of PDOs and PDXs in terms of practicality, ...
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Microtubule-associated NAV3 regulates invasive phenotypes in glioblastoma cells
original article
open access
published version
2025
,Brain Pathology
,35
(1)
Glioblastomas are aggressive brain tumors for which effective therapy is still lacking, resulting in dismal survival rates. These tumors display significant phenotypic plasticity, harboring diverse cell populations ranging ...
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Circulating perturbation of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) is associated to cardiac remodeling and NLRP3 inflammasome in cardiovascular patients with insulin resistance risk
original article
open access
published version
2024
,Experimental and Molecular Pathology
,137
(June)
Lipidome perturbation occurring during meta -inflammation is associated to left ventricle (LV) remodeling though the activation of the NLRP3 inflammasome, a key regulator of chronic inflammation in obesity -related disorders. ...
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Electrical remodeling of atrioventricular junction: a study on retrogradely perfused chick embryonic heart
original article
open access
published version
2024
,American Journal of Physiology - Heart and Circulatory Physiology
,327
(3)
Atrioventricular (AV) accessory pathways (APs) provide additional electrical connections between the atria and ventricles, resulting in severe electrical disturbances. It is generally accepted that APs originate in the ...
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Incorporating high-resolution climate, remote sensing and topographic data to map annual forest growth in central and eastern Europe
original article
open access
published version
2024
,Science of the Total Environment
,913
(February)
To enhance our understanding of forest carbon sequestration, climate change mitigation and drought impact on forest ecosystems, the availability of high-resolution annual forest growth maps based on tree-ring width (TRW) ...
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Expanding clinical spectrum of PAICS deficiency: Comprehensive analysis of two sibling cases
original article
open access
published version
2024
,European Journal of Human Genetics
,AHEAD OF PRINT
(Published online: 27 November 2024)
De novo synthesis of purines (DNPS) is a biochemical pathway that provides the purine bases for synthesis of essential biomolecules such as nucleic acids, energy transfer molecules, signaling molecules and various cofactors. ...
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Local diversity of soil forming processes in the semi-arid tropics and its environmental drivers: An example from Otavi Mountains, northern Namibia
original article
open access
published version
2025
,Catena
,249
(February)
Local diversity of soil units and properties in a semi-arid tropical climate is controlled by a number of interacting factors, whose contribution to the final form of individual soil characteristics is often difficult to ...
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Clinical Features, Outcomes, and Response to Corticosteroid Treatment of Acute Tubulointerstitial Nephritis: A Single-Centre Retrospective Cohort Study in the Czech Republic
original article
open access
published version
2024
,Kidney & Blood Pressure Research
,49
(1)
Introduction: Acute tubulointerstitial nephritis (ATIN) is a well-recognized cause of acute kidney injury (AKI) due to the tubulointerstitial inflammation. The aim of this study was to explore the clinical features, outcomes, ...
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Arsenic bioaccessibility in environmentally important arsenic minerals
original article
open access
published version
2025
,Journal of Hazardous Materials
,485
(March)
The potential risk to humans from incidental ingestion of As-contaminated soil and mine waste is influenced by the mineralogical composition of the As phases present. Using the Solubility Bioaccessibility Research Consortium ...
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Health Problems of Civilization Physical activity: diseases and issues recognized by the WHO
original article
open access
published version
2024
,Health Problems of Civilization
,18
(2)
Background. The aim of the work was to ascertain the differences in the temporal characteristics of the gait cycle of slow walking in high heels. The study particularly focusedon a group of women who started to wear high ...
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Metabolism of primary high-grade serous ovarian carcinoma (HGSOC) cells under limited glutamine or glucose availability
original article
open access
published version
2024
,Cancer & Metabolism
,12
(September)
BackgroundHigh-grade serous ovarian carcinoma (HGSOC) is the most common and aggressive subtype of epithelial ovarian carcinoma. It is primarily diagnosed at stage III or IV when the 5-year survival rate ranges between 20% ...
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Compensatory exercises for young cyclists in the pubescents
original article
open access
published version
2024
,Physical Activity Review
,12
(1)
The aim of the study was to evaluate the state of the musculoskeletal system of selectedcyclists and to propose appropriate compensatory exercises, the effects of which were verified inpractice. Twenty-eight MTB cyclists ...
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Revising pathogenesis of AP1S1-related MEDNIK syndrome: a missense variant in the AP1S1 gene as a causal genetic lesion
original article
open access
published version
2024
,Journal of Molecular Medicine
,102
(11)
MEDNIK syndrome is a rare autosomal recessive disease characterized by mental retardation, enteropathy, deafness, peripheral neuropathy, ichthyosis, and keratoderma, and caused by variants in the adaptor-related protein ...
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Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patients
original article
open access
published version
2024
,Molecular Cancer
,23
(1)
BACKGROUND: The BCR::ABL1 is a hallmark of chronic myeloid leukemia (CML) and is also found in acute lymphoblastic leukemia (ALL). Most genomic breaks on the BCR side occur in two regions - Major and minor - leading to ...
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Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase
original article
open access
published version
2024
,Cancer Letters
,605
(November)
Tumor cells often adapt to amino acid deprivation through metabolic rewiring, compensating for the loss with alternative amino acids/substrates. We have described such a scenario in leukemic cells treated with L-asparaginase ...
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Mouse polyomavirus infection induces lamin reorganisation
original article
open access
published version
2024
,FEBS Journal
,291
(23)
The nuclear lamina is a dense network of intermediate filaments beneath the inner nuclear membrane. Composed of A-type lamins (lamin A/C) and B-type lamins (lamins B1 and B2), the nuclear lamina provides a scaffold for the ...
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Italian peninsula as a hybridization zone of Ixodes inopinatus and I. ricinus and the prevalence of tick-borne pathogens in I. inopinatus, I. ricinus, and their hybrids
original article
open access
published version
2024
,Parasites & Vectors
,17
(1)
BACKGROUND: Ixodes inopinatus was described from Spain on the basis of morphology and partial sequencing of 16S ribosomal DNA. However, several studies suggested that morphological differences between I. inopinatus and ...