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Novel autophagy inducer inhibits hepatitis B virus S antigen secretion

dc.contributor.authorŠmahelová, Zuzana
dc.contributor.authorPimková Polidarová, Markéta
dc.contributor.authorSedláček, Jindřich
dc.contributor.authorBerehovska, Olena
dc.contributor.authorJanovec, Václav
dc.contributor.authorAdámek, Michael
dc.contributor.authorHirsch, Ivan
dc.contributor.authorMachara, Aleš
dc.contributor.authorGrantz Šašková, Klára
dc.date.accessioned2024-10-14T08:47:03Z
dc.date.available2024-10-14T08:47:03Z
dc.date.issued2024
dc.identifier.urihttps://hdl.handle.net/20.500.14178/2653
dc.description.abstractChronic hepatitis B (CHB), a liver infection caused by the hepatitis B virus (HBV), affects more than 300 million people worldwide. If left untreated, CHB can progress to liver cirrhosis and hepatocellular carcinoma, resulting in over 800,000 deaths annually. While current therapies based on nucleot(s)ide analogues effectively slow disease progression and reduce viral load, they require lifelong adinistration. Pegylated interferon alpha therapy can achieve clearance in a small fraction of patients but is associated with significant side effects.en
dc.language.isoen
dc.publisherČeská společnost chemická
dc.rightsCreative Commons Uveďte původ 4.0 Internationalcs
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.titleNovel autophagy inducer inhibits hepatitis B virus S antigen secretionen
dcterms.accessRightsopenAccess
dcterms.licensehttps://creativecommons.org/licenses/by/4.0/legalcode
dc.date.updated2024-10-14T08:47:03Z
dc.subject.keywordHepatitis Ben
dc.subject.keywordHBsAgen
dc.subject.keywordchronicen
dc.identifier.eissn2336-7210
dc.relation.fundingReferenceinfo:eu-repo/grantAgreement/MSM//LX22NPO5103
dc.relation.fundingReferenceinfo:eu-repo/grantAgreement/UK/COOP/COOP
dc.date.embargoStartDate2024-10-14
dc.type.obd110
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dc.identifier.obd653746
dc.subject.rivPrimary10000::10600
dcterms.isPartOf.nameCzech Chemical Society Symposium Series
dcterms.isPartOf.issn2336-7202
dcterms.isPartOf.journalYear2024
dcterms.isPartOf.journalVolume22
dcterms.isPartOf.journalIssue6
uk.faculty.primaryId115
uk.faculty.primaryNamePřírodovědecká fakultacs
uk.faculty.primaryNameFaculty of Scienceen
uk.department.primaryId1034
uk.department.primaryNameKatedra genetiky a mikrobiologiecs
uk.department.primaryNameDepartment of Genetics and Microbiologyen
uk.event.nameThe third annual meeting of the National Institute of Virology and Bacterology (NIVB)
dc.description.pageRange240-240
dc.type.obdHierarchyCsABSTRAKT::abstrakt::abstrakt v elektronické podoběcs
dc.type.obdHierarchyEnABSTRACT::abstract::abstract in e-formen
dc.type.obdHierarchyCode110::130::136en
uk.displayTitleNovel autophagy inducer inhibits hepatitis B virus S antigen secretionen


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