| dc.contributor.author | Šmahelová, Zuzana | |
| dc.contributor.author | Pimková Polidarová, Markéta | |
| dc.contributor.author | Sedláček, Jindřich | |
| dc.contributor.author | Berehovska, Olena | |
| dc.contributor.author | Janovec, Václav | |
| dc.contributor.author | Adámek, Michael | |
| dc.contributor.author | Hirsch, Ivan | |
| dc.contributor.author | Machara, Aleš | |
| dc.contributor.author | Grantz Šašková, Klára | |
| dc.date.accessioned | 2024-10-14T08:47:03Z | |
| dc.date.available | 2024-10-14T08:47:03Z | |
| dc.date.issued | 2024 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14178/2653 | |
| dc.description.abstract | Chronic hepatitis B (CHB), a liver infection caused by the hepatitis B virus (HBV), affects more than 300 million people worldwide. If left untreated, CHB can progress to liver cirrhosis and hepatocellular carcinoma, resulting in over 800,000 deaths annually. While current therapies based on nucleot(s)ide analogues effectively slow disease progression and reduce viral load, they require lifelong adinistration. Pegylated interferon alpha therapy can achieve clearance in a small fraction of patients but is associated with significant side effects. | en |
| dc.language.iso | en | |
| dc.publisher | Česká společnost chemická | |
| dc.rights | Creative Commons Uveďte původ 4.0 International | cs |
| dc.rights | Creative Commons Attribution 4.0 International | en |
| dc.title | Novel autophagy inducer inhibits hepatitis B virus S antigen secretion | en |
| dcterms.accessRights | openAccess | |
| dcterms.license | https://creativecommons.org/licenses/by/4.0/legalcode | |
| dc.date.updated | 2024-10-14T08:47:03Z | |
| dc.subject.keyword | Hepatitis B | en |
| dc.subject.keyword | HBsAg | en |
| dc.subject.keyword | chronic | en |
| dc.identifier.eissn | 2336-7210 | |
| dc.relation.fundingReference | info:eu-repo/grantAgreement/MSM//LX22NPO5103 | |
| dc.relation.fundingReference | info:eu-repo/grantAgreement/UK/COOP/COOP | |
| dc.date.embargoStartDate | 2024-10-14 | |
| dc.type.obd | 110 | |
| dc.type.version | info:eu-repo/semantics/acceptedVersion | |
| dc.identifier.obd | 653746 | |
| dc.subject.rivPrimary | 10000::10600 | |
| dcterms.isPartOf.name | Czech Chemical Society Symposium Series | |
| dcterms.isPartOf.issn | 2336-7202 | |
| dcterms.isPartOf.journalYear | 2024 | |
| dcterms.isPartOf.journalVolume | 22 | |
| dcterms.isPartOf.journalIssue | 6 | |
| uk.faculty.primaryId | 115 | |
| uk.faculty.primaryName | Přírodovědecká fakulta | cs |
| uk.faculty.primaryName | Faculty of Science | en |
| uk.department.primaryId | 1034 | |
| uk.department.primaryName | Katedra genetiky a mikrobiologie | cs |
| uk.department.primaryName | Department of Genetics and Microbiology | en |
| uk.event.name | The third annual meeting of the National Institute of Virology and Bacterology (NIVB) | |
| dc.description.pageRange | 240-240 | |
| dc.type.obdHierarchyCs | ABSTRAKT::abstrakt::abstrakt v elektronické podobě | cs |
| dc.type.obdHierarchyEn | ABSTRACT::abstract::abstract in e-form | en |
| dc.type.obdHierarchyCode | 110::130::136 | en |
| uk.displayTitle | Novel autophagy inducer inhibits hepatitis B virus S antigen secretion | en |
