dc.contributor.author | Čurila, Karol | |
dc.contributor.author | Jurák, Pavel | |
dc.contributor.author | Prinzen, Frits | |
dc.contributor.author | Jastrzębski, Marek | |
dc.contributor.author | Waldauf, Petr | |
dc.contributor.author | Halámek, Josef | |
dc.contributor.author | Tothová, Markéta | |
dc.contributor.author | Znojilová, Lucie | |
dc.contributor.author | Smíšek, Radovan | |
dc.contributor.author | Karch, Jakub | |
dc.contributor.author | Povišer, Lukáš | |
dc.contributor.author | Línková, Hana | |
dc.contributor.author | Plešinger, Filip | |
dc.contributor.author | Moskal, Pawel | |
dc.contributor.author | Viščor, Ivo | |
dc.contributor.author | Vondra, Vlastimil | |
dc.contributor.author | Leinveber, Pavel | |
dc.contributor.author | Osmančík, Pavel | |
dc.date.accessioned | 2023-12-28T10:40:41Z | |
dc.date.available | 2023-12-28T10:40:41Z | |
dc.date.issued | 2023 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14178/2144 | |
dc.description.abstract | BACKGROUND: Left bundle branch pacing (LBBP) produces delayed, unphysiological activation of the right ventricle. Using ultra-high-frequency electrocardiography (UHF-ECG), we explored how bipolar anodal septal pacing with direct LBB capture (aLBBP) affects the resultant ventricular depolarization pattern. METHODS: In patients with bradycardia, His bundle pacing (HBP), unipolar nonselective LBBP (nsLBBP), aLBBP, and right ventricular septal pacing (RVSP) were performed. Timing of local ventricular activation, in leads V1-V8, was displayed using UHF-ECG, and electrical dyssynchrony (e-DYS) was calculated as the difference between the first and last activation. Durations of local depolarizations were determined as the width of the UHF-QRS complex at 50% of its amplitude. RESULTS: aLBBP was feasible in 63 of 75 consecutive patients with successful nsLBBP. aLBBP significantly improved ventricular dyssynchrony (mean -9 ms; 95% CI (-12;-6) vs. -24 ms (-27;-21), ), p < 0.001) and shortened local depolarization durations in V1-V4 (mean differences -7 ms to -5 ms (-11;-1), p < 0.05) compared to nsLBBP. aLBBP resulted in e-DYS -9 ms (-12; -6) vs. e-DYS 10 ms (7;14), p < 0.001 during HBP. Local depolarization durations in V1-V2 during aLBBP were longer than HBP (differences 5-9 ms (1;14), p < 0.05, with local depolarization duration in V1 during aLBBP being the same as during RVSP (difference 2 ms (-2;6), p = 0.52). CONCLUSION: Although aLBBP improved ventricular synchrony and depolarization duration of the septum and RV compared to unipolar nsLBBP, the resultant ventricular depolarization was still less physiological than during HBP. | en |
dc.language.iso | en | |
dc.relation.url | https://doi.org/10.3389/fcvm.2023.1140988 | |
dc.rights | Creative Commons Uveďte původ 4.0 International | cs |
dc.rights | Creative Commons Attribution 4.0 International | en |
dc.title | Bipolar anodal septal pacing with direct LBB capture preserves physiological ventricular activation better than unipolar left bundle branch pacing | en |
dcterms.accessRights | openAccess | |
dcterms.license | https://creativecommons.org/licenses/by/4.0/legalcode | |
dc.date.updated | 2024-04-16T18:40:42Z | |
dc.subject.keyword | His bundle pacing | en |
dc.subject.keyword | LBBP | en |
dc.subject.keyword | anodal septal pacing | en |
dc.subject.keyword | dyssynchrony | en |
dc.subject.keyword | ultra-high-frequency ECG | en |
dc.relation.fundingReference | info:eu-repo/grantAgreement/MSM//LX22NPO5104 | |
dc.relation.fundingReference | info:eu-repo/grantAgreement/UK/COOP/COOP | |
dc.date.embargoStartDate | 2024-04-16 | |
dc.type.obd | 73 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | |
dc.identifier.doi | 10.3389/fcvm.2023.1140988 | |
dc.identifier.utWos | 000963698000001 | |
dc.identifier.eidScopus | 2-s2.0-85152550668 | |
dc.identifier.obd | 626349 | |
dc.identifier.riv | RIV/00216208:11120/23:43925338 | |
dc.identifier.pubmed | 37034324 | |
dc.subject.rivPrimary | 30000::30200::30201 | |
dcterms.isPartOf.name | Frontiers in Cardiovascular Medicine | |
dcterms.isPartOf.issn | 2297-055X | |
dcterms.isPartOf.journalYear | 2023 | |
dcterms.isPartOf.journalVolume | 10 | |
dcterms.isPartOf.journalIssue | March | |
uk.faculty.primaryId | 110 | |
uk.faculty.primaryName | 3. lékařská fakulta | cs |
uk.faculty.primaryName | Third Faculty of Medicine | en |
uk.department.primaryId | 110 | |
uk.department.primaryName | 3. lékařská fakulta | cs |
uk.department.primaryName | Third Faculty of Medicine | en |
uk.department.secondaryId | 634 | |
uk.department.secondaryId | 624 | |
uk.department.secondaryName | Kardiologická klinika 3. LF UK a FNKV | cs |
uk.department.secondaryName | Department of Cardiology 3FM CU and UHKV | en |
uk.department.secondaryName | Klinika anesteziologie a resuscitace 3. LF UK a FNKV | cs |
uk.department.secondaryName | Department of Anaesthesia and Intensive Care Medicine 3FM CU and UHKV | en |
dc.type.obdHierarchyCs | ČLÁNEK V ČASOPISU::článek v časopisu::původní článek | cs |
dc.type.obdHierarchyEn | JOURNAL ARTICLE::journal article::original article | en |
dc.type.obdHierarchyCode | 73::152::206 | en |
uk.displayTitle | Bipolar anodal septal pacing with direct LBB capture preserves physiological ventricular activation better than unipolar left bundle branch pacing | en |