Repozitář publikační činnosti UK: Poslední příspěvky
Zobrazují se záznamy 361-380 z 1467
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Infekce lidským papilomavirem (HPV) a gravidita
Human papillomavirus (HPV) infection and pregnancy
původní článek
open access
vydavatelská verze
2024
,Epidemiologie, mikrobiologie, imunologie
,73
(1)
Lidský papilomavirus (HPV) je celosvětově nejběžnější sexuálně přenosnou virovou infekcí, která může vést ke vzniku benigních lézí nebo maligních nádorů. Prevalence HPV infekce je u těhotných žen dvakrát vyšší než u ...
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Enhancing Proteasome Function Through NRF1 Activation: Novel Small-Molecule Compounds for Treating Neurodegenerative Diseases
abstrakt v elektronické podobě
open access
preprint
2024
The degradation of intracellular proteins is a strictly regulated process vital formaintaining cellular homeostasis and ensuring optimal functionality of the cell. Over90% of cytosolic proteins undergo degradation via the ...
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Analysis of the yeast linear plasmid mRNAs revealed unusual addition of the non-template nucleotides to their 5' ends and suggested a novel mechanism of translation initiation
abstrakt v elektronické podobě
open access
vydavatelská verze
2024
,Abstracts of papers presented at the 2024 meeting on TRANSLATIONAL CONTROL
Linear plasmids were found in a number of yeast species belonging to nine genera. The Kluyveromyces lactis pGKL1/2 plasmids, which serve as archetypes of yeast linear plasmids, are peculiar in many respects. Both plasmids ...
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Myocardial regeneration after embryonic cryoinjury influenced by epicardium
poster
open access
preprint
2023
One of the unexplored topics of medicine that could significantly affect the treatment of myocardial infarction is the regenerative potential of the epicardium. The embryonic epicardium is the outermost layer of the heart, ...
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Dystonia: A novel sign of the Smith-Magenis syndrome – A three-case report
kazuistika
open access
vydavatelská verze
2024
,Clinical Parkinsonism & Related Disorders
,11
(August)
The Smith-Magenis syndrome (SMS) is a rare genetic disorder caused by a microdeletion in the 17p11.2. region or a pathogenic variant of the RAI1 (retinoic acid-induced), which is located in the 17p11.2 area. In most cases, ...
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Hölderlinovy básně z prvního období ve věži
Hölderlin´s Poems form the first Period in the Tower
původní článek
open access
vydavatelská verze
2024
,Svět literatury
,34
(70)
České résumé: Článek je věnován básním německého básníka Friedricha Hölderlina, které psal po své propuštění z kliniky, tj. přibližně v letech 1807 až 1820. Autor se pokouší dokázat, že texty z této doby, které řadí do ...
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ADAR1 knockout leads to global deregulation of translation and to translational shutdown upon IFN-α/β treatment in human Huh7.5 hepatocytes
abstrakt v elektronické podobě
open access
vydavatelská verze
2024
,Abstracts of papers presented at the 2024 meeting on TRANSLATIONAL CONTROL
In recent years, numerous evidence has been accumulated about the extent of A-to-I editing in human RNAs and the key role ADAR1 plays in the cellular editing machinery. It has been shown that A-to-I editing occurrence and ...
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Cannabidiol disrupts tryptophan metabolism in the human term placenta
původní článek
open access
vydavatelská verze
2024
,Toxicology
,505
(June)
The increasing use of cannabis during pregnancy raises concerns about its impact on fetal development. While cannabidiol (CBD) shows therapeutic promise, its effects during pregnancy remain uncertain. We investigated CBD's ...
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Metformin inhibits OCT3-mediated serotonin transport in the placenta
původní článek
open access
vydavatelská verze
2024
,Biomedicine & Pharmacotherapy
,179
(October)
Proper fetal development requires tight regulation of serotonin concentrations within the fetoplacental unit. This homeostasis is partly maintained by the placental transporter OCT3/SLC22A3, which takes up serotonin from ...
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Developmental expression of catecholamine system in the human placenta and rat fetoplacental unit
původní článek
open access
vydavatelská verze
2024
,Scientific Reports
,14
(1)
Catecholamines norepinephrine and dopamine have been implicated in numerous physiological processes within the central nervous system. Emerging evidence has highlighted the importance of tightly regulated monoamine levels ...
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Understanding the effect of term limits on voter turnout: Evidence from a quasi-experiment in Costa Rica based on a registered report
původní článek
open access
vydavatelská verze
2024
,Research & Politics
,11
(3)
Imposing term limits on elected officials is expected to increase turnout due to enhanced competition by one theoretical perspective, while another predicts depressed turnout as a result of clientelist turnout buying. These ...
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Akutní infarkt myokardu a preexistující levostranné chlopenní vady
přednáška
open access
vydavatelská verze
2024
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Survival in Thyroid Cancer in Sweden From 1999 To 2018
původní článek
open access
vydavatelská verze
2024
,Clinical Epidemiology
,16
(2 October 2024)
INTRODUCTION: Thyroid cancer (TC) is diagnosed in several histological types which differ in their clinical characteristics and survival. We aim to describe how they influence TC survival in Sweden. METHODS: Cancer data ...
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Complex Relationships between Diagnostics and Survival in Chronic Lymphocytic Leukemia in Denmark, Finland, Norway, and Sweden
původní článek
open access
vydavatelská verze
2024
,Cancers
,16
(18)
BACKGROUND: Chronic lymphocytic leukemia (CLL) is a common hematological malignancy with highly variable clinical presentation. Many patients never require any treatment but for the others, chemotherapy, immunochemotherapy, ...
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A novel F type plasmid encoding mcr-10 in a clinical Enterobacter ludwigii strain from a tertiary hospital in Czech Republic
původní článek
open access
vydavatelská verze
2024
,Journal of Global Antimicrobial Resistance
,37
(June)
Objective: Here we describe a novel IncFIA plasmid harboring mcr-10 gene in a clinical Enterobacter ludwigii strain isolated at the University Hospital in Pilsen in the Czech Republic.Methods: The strain was subjected to ...
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Percutaneous transthoracic needle biopsy of lung lesions is a safe method associated with a very low risk of pleural recurrence
původní článek
open access
vydavatelská verze
2025
,Biomedical Papers
,169
(1)
AIM: Percutaneous transthoracic needle biopsy (PTNB), an alternative to bronchoscopic confirmation of lung lesions, is today being associated with a risk of pneumothorax and hemorrhage. Further, there are no data on the ...
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Emergence of Escherichia coli ST131 carrying carbapenemase genes, European Union/European Economic Area, August 2012 to May 2024
původní článek
open access
postprint
2024
,Eurosurveillance
,29
(47)
Analysis of 594 isolates of Escherichia coli sequence type (ST)131 and its single locus variants carrying carbapenemase genes from 17 European Union/European Economic Area countries revealed acquisition of 18 carbapenemase ...
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Geldanamycin, a Naturally Occurring Inhibitor of Hsp90 and a Lead Compound for Medicinal Chemistry
přehledový článek
open access
vydavatelská verze
2024
,Journal of Medicinal Chemistry
,67
(20)
Geldanamycin remains a driver in the medicinal chemistry of heat shock protein 90 (Hsp90) inhibition, even half a century after its original isolation from nature. This Perspective focuses on the properties of the benzoquinone ...
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Tetralogy of Fallot: Physiological and morphological changes in conditional Jagged1 mutant mice
poster
open access
vydavatelská verze
2024
The Notch signaling pathway is an evolutionarily conserved intercellular signaling mechanism essential for embryonic development in mammals. Mutations in the human Jagged1 (Jag1) gene, which encodes a ligand for the Notch, ...
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The Difference between Total and Inexact Differential Using 3D Printing Technology and LEGO© Bricks: Application on the First Law of Thermodynamics
abstrakt v konferenčním sborníku
open access
postprint
2022
,Wroclaw
,Institute of Experimental Physics, University of Wrocław
,25th International Workshop on Multimedia in Physics Teaching and Learning - Bookof Abstracts
The poster presents two educational kits created with the help of 3D printing technology. Both kits are used as a part of the course of advanced thermodynamics aimed specially at future high school teachers. The kits deal ...
