Repozitář publikační činnosti UK: Poslední příspěvky

Zobrazují se záznamy 21-40 z 1574

    • Prognostic Role of Prostate-specific Antigen Isoforms and Their Early Kinetics in Patients With Metastatic Castration-resistant Prostate Cancer Receiving New Generation Androgen Receptor Targeted Agents 

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      Fiala, Ondřej

      ;

      Hošek, Petr

      ;

      Korunková, Hana

      ;

      Tkadlecová, Michaela

      ;

      Hora, Milan

      ;

      Šiková, Dominika

      ;

      Stránský, Petr

      ;

      Fínek, Jindřich

      ;

      Kučera, Radek

      ;

      Windrichová, Jindra

      ;

      Topolčan, Ondřej

      2025

      ,

      Iōannīs G. Delīnasios

      ,

      In Vivo

      ,

      39

      (2)

      BACKGROUND/AIM: New generation androgen receptor-targeting agents (ARTA) have been in the spotlight for their efficacy in metastatic castration-resistant prostate cancer (mCRPC). Prostate-specific antigen (PSA) represents ...

    • Impact of concomitant use of proton pump inhibitors or cardiovascular medication on survival outcomes of patients with metastatic renal cell carcinoma treated with nivolumab 

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      Fiala, Ondřej

      ;

      Hošek, Petr

      ;

      Tkadlecová, Michaela

      ;

      Melichar, Bohuslav

      ;

      Zemánková, Anežka

      ;

      Kopecký, Jindřich

      ;

      Vočka, Michal

      ;

      Matějů, Martin

      ;

      Lohynská, Radka

      ;

      Šiková, Dominika

      ;

      Stránský, Petr

      ;

      Študentová, Hana

      ;

      Spisarová, Martina

      ;

      Nováková, Hana

      ;

      Priester, Peter

      ;

      Kryštofová, Dominika

      ;

      Grmelová, Lucie

      ;

      Büchler, Tomáš

      ;

      Poprach, Alexandr

      2025

      ,

      Clinical & Experimental Metastasis

      ,

      42

      (5)

      Renal cell cancer (RCC) is typically a disease of older adults, who often have comorbidities requiring the use of multiple concomitant medications. Even though the patients with metastatic RCC (mRCC) are often exposed to ...

    • Native and decellularized porcine vena cava: Biomechanical and microstructural comparison 

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      Massaro, Maria Stefania

      ;

      Sommer, Gerhard

      ;

      Pukaluk, Anna

      ;

      Wolinski, Heimo

      ;

      Pálek, Richard

      ;

      Červenková, Lenka

      ;

      Ševčík, Jan

      ;

      Rampitsch, Katharina

      ;

      Bolek, Lukáš

      ;

      Liška, Václav

      ;

      Holzapfel, Gerhard A

      ;

      Moulisová, Vladimíra

      2025

      ,

      Elsevier Ltd.

      ,

      Acta Biomaterialia

      ,

      201

      (July)

      Tissue decellularization has emerged as a technique to provide an acellular, non-immunogenic scaffold that preserves the morphological features of native tissue. To study the possible effects of decellularization, investigating ...

    • Temperature and nutrient availability influence radial growth of Picea abies at opposite slopes in a treeline ecotone 

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      Kuželová, Hana

      ;

      Chuman, Tomáš

      ;

      Lange, Jelena Ana

      ;

      Tumajer, Jan

      ;

      Treml, Václav

      2025

      ,

      Copernicus Publ.

      ,

      Biogeosciences

      ,

      22

      (15)

      Treeline ecotones in complex mountain landscapes are exposed to pronounced differences in irradiation and soil nutrient availability. Different amounts of nutrients and direct solar energy can influence tree stem growth, ...

    • Integrative miRNOMe profiling reveals the miR-195-5p–CHEK1 axis and its impact on luminal breast cancer outcomes 

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      Boušková, Veronika

      ;

      Ehrlichová, Marie

      ;

      Spálenková, Alžběta

      ;

      Krus, Ivona

      ;

      Šůsová, Simona

      ;

      Hlaváč, Viktor

      ;

      Němcová, Vlasta

      ;

      Koževnikovová, Renata

      ;

      Trnková, Markéta

      ;

      Vrána, David

      ;

      Gatěk, Jiří

      ;

      Kopečková, Kateřina

      ;

      Mrhalová, Marcela

      ;

      Měšťáková, Soňa

      ;

      Souček, Pavel

      2025

      ,

      John Wiley & Sons

      ,

      Molecular Oncology

      The luminal subtype (estrogen receptor-positive, ER+) is the most common and the most heterogeneous type of breast carcinoma (BC) in women. During our study, we determined expression levels of all microRNAs (miRNome) in ...

    • Prioritization of predisposition genes for familial non-medullary thyroid cancer by whole-genome sequencing 

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      Srivastava, Aayushi

      ;

      Skopelitou, Diamanto

      ;

      Miao, Beiping

      ;

      Giagiobbe, Sara

      ;

      Paramasivam, Nagarajan

      ;

      Kumar, Abhishek

      ;

      Diquigiovanni, Chiara

      ;

      Bonora, Elena

      ;

      Bandapalli, Obul Reddy

      ;

      Försti, Asta

      ;

      Hemminki, Kari Jussi

      2025

      ,

      BioScientifica

      ,

      European Journal of Endocrinology

      ,

      192

      (4)

      OBJECTIVE: Thyroid cancer (TC) is the most common endocrine malignancy, with 90%-95% of the cases representing non-medullary thyroid cancer (NMTC). Familial cases account only for a few of all cases and the underlying ...

    • Association of long-term treatment outcomes with changes in PET/MRI characteristics and the type of early treatment response during concurrent radiochemotherapy in patients with locally advanced cervical cancer 

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      Vojtíšek, Radovan

      ;

      Baxa, Jan

      ;

      Hošek, Petr

      ;

      Kovářová, Petra

      ;

      Vítovec, Martin

      ;

      Sukovská, Emília

      ;

      Kosťun, Jan

      ;

      Vlasák, Pavel

      ;

      Presl, Jiří

      ;

      Ferda, Jiří

      ;

      Fínek, Jindřich

      2025

      ,

      Urban u. Vogel

      ,

      Strahlentherapie und Onkologie

      ,

      201

      (5)

      PURPOSE: We aimed to find predictive tumour characteristics as detected by interim positron-emission tomography/magnetic resonance imaging (PET/MRI) in cervical cancer patients. We also investigated the type of interim ...

    • Agonistic Spaces: Dissensus and Ethical Conflicts in Recent Irish Theatre 

      kapitola v kolektivní monografii

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      Wallace, Clare

      2025

      ,

      Abingdon

      ,

      Routledge, part of the Taylor & Francis Group

      ,

      The Routledge Companion to 21st Century Irish Writing

      This chapter explores agonistic encounters in Irish theatre. Positioning its discussion in relation to the wider Irish theatre context in the first decades of the twenty-first century, the chapter foregrounds three recent ...

    • Genetic Testing for Malformations of Cortical Development 

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      Straka, Barbora

      ;

      Heřmanovská, Barbora

      ;

      Krsková, Lenka

      ;

      Zámečník, Josef

      ;

      Vlčková, Markéta

      ;

      Balaščaková, Miroslava

      ;

      Tesner, Pavel

      ;

      Jezdik, Petr

      ;

      Tichý, Michal

      ;

      Kynčl, Martin

      ;

      Musilová, Alena

      ;

      Laššuthová, Petra

      ;

      Marusič, Petr

      ;

      Kršek, Pavel

      ;

      Kudr, Martin

      ;

      Bělohlávková, Anežka

      ;

      Ebel, Matyáš

      ;

      Jahodová, Alena

      ;

      Kalinová, Markéta

      ;

      Novak, Vilem

      ;

      Rivera, Gonzalo Alonso Ramos

      ;

      Staněk, David

      ;

      Libý, Petr

      ;

      Kalina, Adam

      ;

      Zárubová, Jana

      ;

      Uhrová Mészárosová, Anna

      ;

      Maulisová, Alice

      ;

      Zůnová, Hana

      ;

      Koblížek, Miroslav

      2022

      ,

      Neurology. Genetics

      ,

      8

      (5)

      Background and Objectives. Malformations of cortical development (MCD), though individually rare, constitute a significant burden of disease. The diagnostic yield of next-generation sequencing (NGS) in these patients varies ...

    • Search for germline gene variants in colorectal cancer families presenting with multiple primary colorectal cancers 

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      Försti, Asta

      ;

      Ambrożkiewicz, Filip

      ;

      Marciniak, Magdalena

      ;

      Lubinski, Jan

      ;

      Hemminki, Kari Jussi

      2025

      ,

      Wiley-Liss

      ,

      International Journal of Cancer

      ,

      156

      (7)

      A double primary colorectal cancer (CRC) in a familial setting signals a high risk of CRC. In order to identify novel CRC susceptibility genes, we whole-exome sequenced germline DNA from nine persons with a double primary ...

    • Age-specific familial risks in cancer as clues to germline genetic and environmental causes: focus on colorectal, endometrial, prostate, kidney, breast and lung cancers 

      přehledový článek

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      Hemminki, Kari Jussi

      ;

      Försti, Asta

      ;

      Hemminki, Otto

      ;

      Scott, Rodney J

      ;

      Hemminki, Akseli

      2025

      ,

      Termedia

      ,

      Hereditary Cancer in Clinical Practice

      ,

      23

      (1)

      BACKGROUND: The Swedish Family-Cancer Database (FCD) is the largest source of data on familial cancer in the world, including practically complete family structures and individual cancer diagnoses from the high-quality ...

    • Is autism driven by epilepsy in infants with Tuberous Sclerosis Complex? 

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      Moavero, Romina

      ;

      Kotulska, Katarzyna

      ;

      Lagae, Lieven

      ;

      Benvenuto, Arianna

      ;

      Emberti Gialloreti, Leonardo

      ;

      Weschke, Bernhard

      ;

      Riney, Kate

      ;

      Feucht, Martha

      ;

      Kršek, Pavel

      ;

      Nabbout, Rima

      ;

      Jansen, Anna C

      ;

      Wojdan, Konrad

      ;

      Borkowska, Julita

      ;

      Sadowski, Krzysztof

      ;

      Hertzberg, Christoph

      ;

      Van Schooneveld, Monique M

      ;

      Samueli, Sharon

      ;

      Maulisová, Alice

      ;

      Aronica, Eleonora

      ;

      Kwiatkowski, David J

      ;

      Jansen, Floor E

      ;

      Jozwiak, Sergiusz

      ;

      Curatolo, Paolo

      2020

      ,

      Annals of Clinical and Translational Neurology [online]

      ,

      7

      (8)

      OBJECTIVE: To evaluate the relationship between age at seizure onset and neurodevelopmental outcome at age 24 months in infants with TSC, as well as the effect on neurodevelopmental outcome of early versus conventional ...

    • miRNAs and isomiRs: Serum-Based Biomarkers for the Development of Intellectual Disability and Autism Spectrum Disorder in Tuberous Sclerosis Complex 

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      Scheper, Mirte

      ;

      Romagnolo, Alessia

      ;

      Besharat, Zein Mersini

      ;

      Iyer, Anand M

      ;

      Moavero, Romina

      ;

      Hertzberg, Christoph

      ;

      Weschke, Bernhard

      ;

      Riney, Kate

      ;

      Feucht, Martha

      ;

      Scholl, Theresa

      ;

      Petrák, Bořivoj

      ;

      Maulisová, Alice

      ;

      Nabbout, Rima

      ;

      Jansen, Anna C

      ;

      Jansen, Floor E

      ;

      Lagae, Lieven

      ;

      Urbanska, Malgorzata

      ;

      Ferretti, Elisabetta

      ;

      Tempes, Aleksandra

      ;

      Blazejczyk, Magdalena

      ;

      Jaworski, Jacek

      ;

      Kwiatkowski, David J

      ;

      Jozwiak, Sergiusz

      ;

      Kotulska, Katarzyna

      ;

      Sadowski, Krzysztof

      ;

      Borkowska, Julita

      ;

      Curatolo, Paolo

      ;

      Mills, James D

      ;

      Aronica, Eleonora

      2022

      ,

      Biomedicines [online]

      ,

      10

      (8)

      Tuberous sclerosis complex (TSC) is a rare multi-system genetic disorder characterized by a high incidence of epilepsy and neuropsychiatric manifestations known as tuberous-sclerosis-associated neuropsychiatric disorders ...

    • Meeting summary of The NYO3 5th NO-Age/AD meeting and the 1st Norway-UK joint meeting on ageing and dementia: recent progress on the mechanisms and interventional strategies 

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      Wang, He-Ling

      ;

      Siow, Richard

      ;

      Schmauck-Medina, Tomas

      ;

      Zhang, Jianying

      ;

      Sandset, Per Morten

      ;

      Filshie, Clare

      ;

      Lund, Øystein

      ;

      Partridge, Linda

      ;

      Bergersen, Linda Hildegard

      ;

      Juel Rasmussen, Lene

      ;

      Palikaras, Konstantinos

      ;

      Sotiropoulos, Ioannis

      ;

      Storm-Mathisen, Jon

      ;

      Rubinsztein, David C

      ;

      Spillantini, Maria Grazia

      ;

      De Zeeuw, Chris I

      ;

      Watne, Leiv Otto

      ;

      Vyhnálek, Martin

      ;

      Veverová, Kateřina

      ;

      Liang, Kristina Xiao

      ;

      Tavernarakis, Nektarios

      ;

      Bohr, Vilhelm A

      ;

      Yokote, Koutaro

      ;

      Saarela, Janna

      ;

      Nilsen, Hilde

      ;

      Gonos, Efstathios S

      ;

      Scheibye-Knudsen, Morten

      ;

      Chen, Guobing

      ;

      Kato, Hisaya

      ;

      Selbæk, Geir

      ;

      Fladby, Tormod

      ;

      Nilsson, Per

      ;

      Simonsen, Anne

      ;

      Aarsland, Dag

      ;

      Lautrup, Sofie

      ;

      Ottersen, Ole Petter

      ;

      Cox, Lynne S

      ;

      Fang, Evandro F

      2024

      ,

      Journals of Gerontology - Series A Biological Sciences and Medical Sciences

      ,

      79

      (4)

      Unhealthy ageing poses a global challenge with profound healthcare and socioeconomic implications. Slowing down the ageing process offers a promising approach to reduce the burden of a number of age-related diseases, such ...

    • Environmental aspects of wastewater recycling from the point of view of emergent pollutant removal 

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      Šereš, Michal

      ;

      Černá, Tereza

      ;

      Hnátková, Tereza

      ;

      Rozkošný, Miloš

      ;

      Grasserová, Alena

      ;

      Semerád, Jaroslav

      ;

      Němcová, Kateřina

      ;

      Cajthaml, Tomáš

      2025

      ,

      IWA Publishing

      ,

      Water Science and Technology

      ,

      91

      (7)

      This study evaluates the removal efficiency of 15 estrogenic endocrine-disrupting compounds in two operational constructed wetlands with different designs: a hybrid system (constructed wetland A) and a horizontal system ...

    • Does VS30 reflect seismic amplification? Observations from the West Bohemia Seismic Network 

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      Mazanec, Martin

      ;

      Valenta, Jan

      ;

      Málek, Jiří

      2024

      ,

      Kluwer

      ,

      Natural Hazards

      ,

      120

      (13)

      The present study addresses verification of average seismic shear-wave velocity from the surface to a depth of 30 m (V(S30)) as a suitable proxy for a seismic amplification. For this purpose, we used instrumentally homogeneous ...

    • Exploring Virulence Characteristics of Clinical Escherichia coli Isolates from Greece 

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      Gagaletsios, Lazaros A.

      ;

      Kikidou, Elisavet

      ;

      Galbenis, Christos

      ;

      Bitar, Ibrahim

      ;

      Papagiannitsis, Costas C.

      2025

      ,

      MDPI

      ,

      Microorganisms

      ,

      13

      (7)

      The aim of this study was to examine the genetic characteristics that could be associated with the virulence characteristics of Escherichia coli collected from clinical samples. A collection of 100 non-repetitive E. coli ...

    • Comparative genomics of multi-drug resistant Escherichia coli ST131 from human, animal, and environmental sources in the Czech Republic 

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      Růžičková, Michaela

      ;

      Karola, Ivana

      ;

      Nohejl, Tomas

      ;

      Sukkar, Iva

      ;

      Palkovičová, Jana

      ;

      Papousek, Ivo

      ;

      Cummins, Max L.

      ;

      Djordjevic, Steven P.

      ;

      Dolejská, Monika

      2025

      ,

      Ecotoxicology and Environmental Safety

      ,

      299

      (July)

      Globally, Escherichia coli is a leading cause of multiple drug-resistant (MDR) extraintestinal infections. ST131 is an MDR, pandemic sequence type that causes urinary tract and bloodstream infections in humans and companion ...

    • The Pattern and the Image in Plotinus: Rethinking Plato’s Conflict with the Poets 

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      Gál, Ota

      2025

      ,

      Berlin

      ,

      De Gruyter

      ,

      The Pattern and the Image: Insights from the Alexandrian Exegetical Tradition

      This paper presents parallels between Plato's and Plotinus' understanding of the notion of an image within the context of the arts and cosmology. It argues for the rejection of the widespread cliché according to which ...

    • Not-so-Failing Junior Partner: Re-examining the AEF's Chemical Warfare Experience before and during the German Spring Offensives 

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      Klepárník, Vít

      2025

      ,

      War in History

      ,

      32

      (1)

      This study, using the revisionist critique of the American Expeditionary Forces (AEF), reopens the issue of US involvement in the ever-engaging field of World War I chemical warfare. It disputes revisionist claims of a ...