Zobrazují se záznamy 1581-1600 z 2051

    • Creating a cell line suitable for investigation into the ADAR1 role in hepatitis C virus replication 

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      Roučová, Kristina

      ;

      Vopálenský, Václav

      ;

      Mašek, Tomáš

      ;

      Del Llano, Edgar

      ;

      Provazník, Jan

      ;

      Landry, Jonathan J.M.

      ;

      Azeveda, Nayara

      ;

      Ehler, Edvard

      ;

      Kubů, Martin

      ;

      Beneš, Vladimír

      ;

      Pospíšek, Martin

      2023

      ,

      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      Adenosine deaminases acting on RNA (ADAR) perform the adenosine to inosine (A-to-I) type of editing. Out of the three human ADAR proteins, ADAR1 is responsible for the majority of A-to-I editing of dsRNA outside the ...

    • Absence of 5' methylguanosine cap in postreplicative genes' transcripts of Vaccinia virus 

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      Vopálenský, Václav

      ;

      Sýkora, Michal

      ;

      Mělková, Zora

      ;

      Barvík, Ivan

      ;

      Mašek, Tomáš

      ;

      Horáčková, Kamila

      ;

      Pospíšek, Martin

      2023

      ,

      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      The Vaccinia virus (VACV) played a pivotal role in the discovery of the 5' mRNA. Over the past decades, VACV investigation has contributed extensively to understanding the mechanism behind 5' mRNA cap synthesis. ...

    • Blood parasites (Trypanosoma, Leucocytozoon, Haemoproteus) in the Eurasian sparrowhawk (Accipiter nisus): diversity, incidence and persistence of infection at the individual level 

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      Svobodová, Milena

      ;

      Čepička, Ivan

      ;

      Zídková, Lenka

      ;

      Kassahun, Aysheshm

      ;

      Votýpka, Jan

      ;

      Peške, Lubomír

      ;

      Hrazdilová, Kristýna

      ;

      Brzoňová, Jana

      ;

      Voříšek, Petr

      ;

      Weidinger, Karel

      2023

      ,

      BioMed Central

      ,

      Parasites & Vectors

      ,

      16

      (1)

      Background :A high prevalence of parasites may result from life-long persistence of infection or from high reinfection rates. We have studied blood parasites in a breeding population of the accipitrid raptor, Eurasian ...

    • Same data, different conclusions: Radical dispersion in empirical results when independent analysts operationalize and test the same hypothesis 

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      Schweinsberg, Martin

      ;

      Feldman, Michael

      ;

      Staub, Nicola

      ;

      van den Akker, Olmo R

      ;

      van Aert, Robbie C. M

      ;

      van Assen, Marcel A. L. M

      ;

      Liu, Yang

      ;

      Althoff, Tim

      ;

      Heer, Jeffrey

      ;

      Kale, Alex

      ;

      Mohamed, Zainab

      ;

      Amireh, Hashem

      ;

      Prasad, Vaishali Venkatesh

      ;

      Bernstein, Abraham

      ;

      Robinson, Emily

      ;

      Snellman, Kaisa

      ;

      Sommer, S. Amy

      ;

      Otner, Sarah M. G

      ;

      Robinson, David

      ;

      Madan, Nikhil

      ;

      Silberzahn, Raphael

      ;

      Goldstein, Pavel

      ;

      Tierney, Warren

      ;

      Murase, Toshio

      ;

      Mandl, Benjamin

      ;

      Viganola, Domenico

      ;

      Strobl, Carolin

      ;

      Schaumans, Catherine B. C

      ;

      Kelchtermans, Stijn

      ;

      Naseeb, Chan

      ;

      Garrison, S. Mason

      ;

      Yarkoni, Tal

      ;

      Chan, C. S. Richard

      ;

      Adie, Prestone

      ;

      Alaburda, Paulius

      ;

      Albers, Casper

      ;

      Alspaugh, Sara

      ;

      Alstott, Jeff

      ;

      Nelson, Andrew A

      ;

      de la Rubia, Eduardo Arinno

      ;

      Arzi, Adbi

      ;

      Bahnik, Stepan

      ;

      Baik, Jason

      ;

      Balling, Laura Winther

      ;

      Banker, Sachin

      ;

      Baranger, David A. A

      ;

      Barr, Dale J

      ;

      Barros-Rivera, Brenda

      ;

      Bauer, Matt

      ;

      Blaise, Enuh

      ;

      Boelen, Lisa

      ;

      Carbonell, Katerina Bohle

      ;

      Briers, Robert A

      ;

      Burkhard, Oliver

      ;

      Canela, Miguel-Angel

      ;

      Castrillo, Laura

      ;

      Catlett, Timothy

      ;

      Chen, Olivia

      ;

      Clark, Michael

      ;

      Cohn, Brent

      ;

      Coppock, Alex

      ;

      Cuguero-Escofet, Natalia

      ;

      Curran, Paul G

      ;

      Cyrus-Lai, Wilson

      ;

      Dai, David

      ;

      Dalla Riva, Giulio Valentino

      ;

      Danielsson, Henrik

      ;

      Russo, Rosaria de F. S. M

      ;

      de Silva, Niko

      ;

      Derungs, Curdin

      ;

      Dondelinger, Frank

      ;

      de Souza, Carolina Duarte

      ;

      Dube, B. Tyson

      ;

      Dubova, Marina

      ;

      Dunn, Ben Mark

      ;

      Edelsbrunner, Peter Adriaan

      ;

      Finley, Sara

      ;

      Fox, Nick

      ;

      Gnambs, Timo

      ;

      Gong, Yuanyuan

      ;

      Grand, Erin

      ;

      Greenawalt, Brandon

      ;

      Han, Dan

      ;

      Hanel, Paul H. P

      ;

      Hong, Antony B

      ;

      Hood, David

      ;

      Hsueh, Justin

      ;

      Huang, Lilian

      ;

      Hui, Kent N

      ;

      Hultman, Keith A

      ;

      Javaid, Azka

      ;

      Jiang, Lily Ji

      ;

      Jong, Jonathan

      ;

      Kamdar, Jash

      ;

      Kane, David

      ;

      Kappler, Gregor

      ;

      Kaszubowski, Erikson

      ;

      Kavanagh, Christopher M

      ;

      Khabsa, Madian

      ;

      Ropovik, Ivan

      2021

      ,

      Organizational Behavior and Human Decision Processes

      ,

      165

      (1)

      In this crowdsourced initiative, independent analysts used the same dataset to test two hypotheses regarding the effects of scientists' gender and professional status on verbosity during group meetings. Not only the analytic ...

    • Genetic analysis challenges the presence of Ixodes inopinatus in Central Europe: Development of a multiplex PCR to distinguish I. inopinatus from I. ricinus 

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      Hrazdilová, Kristýna

      ;

      Daněk, Ondřej

      ;

      Hrbatová, Alena

      ;

      Červená, Barbora

      ;

      Nosková, Eva

      ;

      Adamík, Peter

      ;

      Votýpka, Jan

      ;

      Mihalca, Andrei Daniel

      ;

      Noureddine, Mechouk

      ;

      Modrý, David

      ;

      Žůrek, Luděk

      2023

      ,

      Parasites & Vectors

      ,

      16

      (1)

      Background Ixodes ricinus is an important vector of several pathogens, primarily in Europe. Recently, Ixodes inopinatus was described from Spain, Portugal, and North Africa and then reported from several European countries. ...

    • Exploring the molecular mechanisms used by human BK polyomavirus to activate immune responses in "reservoir cells" 

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      Bruštíková, Kateřina

      ;

      Rjabčenko, Boris

      ;

      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2023

      ,

      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      At present, the Polyomaviridae family contains 14 human polyomaviruses (PyVs), among the most important are Merkel cell polyomavirus (MCPyV), the etiological agent of 80% of Merkel cell carcinomas, JCPyV and BKPyV causing ...

    • Characterization of a human placental clearance system to regulate serotonin levels in the fetoplacental unit 

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      Štaud, František

      ;

      Pan, Xin

      ;

      Karahoda, Rona

      ;

      Dong, Xiaojing

      ;

      Kastner, Petr

      ;

      Horáčková, Hana

      ;

      Váchalová, Veronika

      ;

      Markert, Udo R.

      ;

      Abad, Cilia

      2023

      ,

      Reproductive Biology and Endocrinology

      ,

      21

      (1)

      Background Serotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated levels of 5-HT in the fetoplacental unit are critical for proper placental ...

    • TET protein inhibitors: Potential and limitations 

      přehledový článek

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      Kaplánek, Robert

      ;

      Kejík, Zdeněk

      ;

      Hajduch, Jan

      ;

      Veselá, Kateřina

      ;

      Kučnirová, Kateřina

      ;

      Skaličková, Markéta

      ;

      Venhauerová, Anna

      ;

      Hosnedlová, Božena

      ;

      Hromádka, Róbert

      ;

      Dytrych, Petr

      ;

      Novotný, Petr

      ;

      Abramenko, Nikita

      ;

      Antonyová, Veronika

      ;

      Hoskovec, David

      ;

      Babula, Petr

      ;

      Masařík, Michal

      ;

      Martásek, Pavel

      ;

      Jakubek, Milan

      2023

      ,

      Biomedicine & Pharmacotherapy

      ,

      166

      (October)

      TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene expression. Dysregulation of their activity is associated with many serious pathogenic states such as oncological diseases. ...

    • Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase 

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      Koudelková, Lenka

      ;

      Pelantová, Markéta

      ;

      Brůhová, Zuzana

      ;

      Sztacho, Martin

      ;

      Pavlík, Vojtěch

      ;

      Pánek, Dalibor

      ;

      Gemperle, Jakub

      ;

      Talacko, Pavel

      ;

      Brábek, Jan

      ;

      Rösel, Daniel

      2023

      ,

      eLife

      ,

      12

      (July)

      The activation of Src kinase in cells is strictly controlled by intramolecular inhibitory interactions mediated by SH3 and SH2 domains. They impose structural constraints on the kinase domain holding it in a catalytically ...

    • Double perovskite Cs2AgBiBr6 radiation sensor: synthesis and characterization of single crystals 

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      Murgulov, Valeria

      ;

      Schweinle, Catherine

      ;

      Daub, Michael

      ;

      Hillebrecht, Harald

      ;

      Fiederle, Michael

      ;

      Dědič, Václav

      ;

      Franc, Jan

      2022

      ,

      Journal of Materials Science [online]

      ,

      57

      (4)

      Single crystals of lead-free halide double perovskite Cs(2)AgBiBr(6) sensor material manifest a remarkable potential for application in radiation detection and imaging. In this study, the purity and crystallinity of ...

    • HBV-induced microenvironment reduces pDC response to TLR7/9 stimulation 

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      Berehovska, Olena

      ;

      Pimková Polidarová, Markéta

      ;

      Janovec, Václav

      ;

      Hirsch, Ivan

      ;

      Grantz Šašková, Klára

      2023

      Hepatitis B virus (HBV) is an infectious agent that causes acute hepatitis, but can also lead to chronic inflammation, and, consequently, to hepatocellular carcinoma. HBV is described as "stealth virus", since it avoids ...

    • Clinical Experience with Autofluorescence Guided Oral Squamous Cell Carcinoma Surgery 

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      Pošta, Petr

      ;

      Kolk, Andreas

      ;

      Pivovarčíková, Kristýna

      ;

      Liška, Jan

      ;

      Genčur, Jiří

      ;

      Moztarzadeh, Omid

      ;

      Micopulos, Christos

      ;

      Pěnkava, Adam

      ;

      Frolo, Mária

      ;

      Bissinger, Oliver

      ;

      Hauer, Lukáš

      2023

      ,

      Diagnostics

      ,

      13

      (20)

      In our study, the effect of the use of autofluorescence (Visually Enhanced Lesion Scope-VELscope) on increasing the success rate of surgical treatment in oral squamous carcinoma (OSCC) was investigated. Our hypothesis was ...

    • Carl Schmitt and Democratic Backsliding 

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      Karolewski, Pawel Ireneusz

      ;

      Libin, Xie

      ;

      Patapan, Haig

      ;

      Halmai, Gabor

      ;

      Kutay, Acar

      ;

      Guasti, Petra

      ;

      Scheuerman, William E.

      2023

      ,

      Contemporary Political Theory

      ,

      22

      (3)

      This Critical Exchange suggests that Schmittian inspirations abound in countries that experience democratic backsliding. Sometimes, Schmitt's ideas are used explicitly, but more often they are implicit in the actions of ...

    • Carl Schmitt and Democratic Backsliding 

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      Karolewski, Pawel Ireneusz

      ;

      Libin, Xie

      ;

      Patapan, Haig

      ;

      Halmai, Gabor

      ;

      Kutay, Acar

      ;

      Guasti, Petra

      ;

      Scheuerman, William E.

      2023

      ,

      Contemporary Political Theory

      ,

      22

      (3)

      This Critical Exchange suggests that Schmittian inspirations abound in countries that experience democratic backsliding. Sometimes, Schmitt's ideas are used explicitly, but more often they are implicit in the actions of ...

    • Acute Effects of Isometric Conditioning Activity on the Viscoelastic Properties of Muscles and Sprint and Jumping Performance in Handball Players 

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      Krzysztofik, Michal

      ;

      Spieszny, Michal

      ;

      Trybulski, Robert

      ;

      Wilk, Michal

      ;

      Pisz, Anna

      ;

      Kolinger, Dominik

      ;

      Filip-Stachnik, Aleksandra

      ;

      Šťastný, Petr

      2023

      ,

      Journal of Strength and Conditioning Research

      ,

      37

      (7)

      Krzysztofik, M, Spieszny, M, Trybulski, R, Wilk, M, Pisz, A, Kolinger, D, Filip-Stachnik, A, and Stastny, P. Acute effects of isometric conditioning activity on the viscoelastic properties of muscles and sprint and jumping ...

    • Sleep quality and sleep routines as mediators of stressors and life satisfaction in Czech university students: a structural equation model 

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      Prokeš, Michaela

      2023

      ,

      Frontiers in Psychology

      ,

      2023

      (14)

      Introduction: Sleep is especially important to overall well-being. Some aspects of sleep have been well documented, for example sleep quantity and its effect on well-being, but the value of a consistent sleep routine remains ...

    • Reliability of the saliva self-sampling with and without supervision 

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      Jaklová Dytrtová, Jana

      ;

      Dytrtová, Radmila

      ;

      Kovač, Ishak

      ;

      Šteffl, Michal

      ;

      Jakl, Michal

      2023

      ,

      Acta Universitatis Carolinae. Kinanthropologica

      ,

      59

      (1)

      One of the least invasive sampling methods suitable for self-sampling is saliva spitting. The aim of this study is to evaluate the suitability of saliva self-sampling for unsupervised testing. Two self-sampling strategies ...

    • Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia 

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      Woodward, Eleanor L

      ;

      Yang, Minjun

      ;

      Moura-Castro, Larissa H

      ;

      van den Bos, Hilda

      ;

      Gunnarsson, Rebeqa

      ;

      Olsson-Arvidsson, Linda

      ;

      Spierings, Diana C J

      ;

      Castor, Anders

      ;

      Duployez, Nicolas

      ;

      Žaliová, Markéta

      ;

      Zuna, Jan

      ;

      Johansson, Bertil

      ;

      Foijer, Floris

      ;

      Paulsson, Kajsa

      2023

      ,

      Nature Communications

      ,

      14

      (1)

      High hyperdiploid acute lymphoblastic leukemia (HeH ALL), one of the most common childhood malignancies, is driven by nonrandom aneuploidy (abnormal chromosome numbers) mainly comprising chromosomal gains. In this study, ...

    • Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome 

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      de Jesus, Adriana A

      ;

      Chen, Guibin

      ;

      Yang, Dan

      ;

      Brdicka, Tomas

      ;

      Ruth, Natasha M

      ;

      Bennin, David

      ;

      Cebecauerová, Dita

      ;

      Malcová, Hana

      ;

      Freeman, Helen

      ;

      Martin, Neil

      ;

      Švojgr, Karel

      ;

      Passo, Murray H

      ;

      Bhuyan, Farzana

      ;

      Alehashemi, Sara

      ;

      Rastegar, Andre T

      ;

      Uss, Katsiaryna

      ;

      Kardava, Lela

      ;

      Marrero, Bernadette

      ;

      Đurić, Iris

      ;

      Omoyinmi, Ebun

      ;

      Peldová, Petra

      ;

      Lee, Chyi-Chia Richard

      ;

      Kleiner, David E

      ;

      Hadigan, Colleen M

      ;

      Hewitt, Stephen M

      ;

      Pittaluga, Stefania

      ;

      Carmona-Rivera, Carmelo

      ;

      Calvo, Katherine R

      ;

      Shah, Nirali

      ;

      Balaščaková, Miroslava

      ;

      Fink, Danielle L

      ;

      Kotalová, Radana

      ;

      Paračková, Zuzana

      ;

      Peterková, Lucie

      ;

      Kužílková, Daniela

      ;

      Campr, Vít

      ;

      Šrámková, Lucie

      ;

      Biancotto, Angelique

      ;

      Brooks, Stephen R

      ;

      Manes, Cameron

      ;

      Meffre, Eric

      ;

      Harper, Rebecca L

      ;

      Kuehn, Hyesun

      ;

      Kaplan, Mariana J

      ;

      Brogan, Paul

      ;

      Rosenzweig, Sergio D

      ;

      Merchant, Melinda

      ;

      Deng, Zuoming

      ;

      Huttenlocher, Anna

      ;

      Moir, Susan L

      ;

      Kuhns, Douglas B

      ;

      Boehm, Manfred

      ;

      Škvárová Kramarzová, Karolina

      ;

      Goldbach-Mansky, Raphaela

      2023

      ,

      Nature Communications

      ,

      14

      (1)

      Neutrophilic inflammation is a hallmark of many monogenic autoinflammatory diseases; pathomechanisms that regulate extravasation of damaging immune cells into surrounding tissues are poorly understood. Here we identified ...

    • STING agonists induce robust cytokine secretion and rapid monocyte cell death in peripheral blood mononuclear cells 

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      Pimková Polidarová, Markéta

      ;

      Hirsch, Ivan

      ;

      Brázdová, Andrea

      ;

      Grantz Šašková, Klára

      2023

      The cyclic-GMP-AMP synthase - stimulator of interferon genes (cGAS-STING) pathway plays a central role in recognition of the double-stranded DNA in cytoplasm, a sign of cell damage or infection. Upon activation, the pathway ...