Repozitář publikační činnosti UK: Poslední příspěvky
Zobrazují se záznamy 1581-1600 z 2051
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Creating a cell line suitable for investigation into the ADAR1 role in hepatitis C virus replication
abstrakt v konferenčním sborníku
open access
postprint
2023
,Czech Chemical Society Symposium Series
,21
(5)
Adenosine deaminases acting on RNA (ADAR) perform the adenosine to inosine (A-to-I) type of editing. Out of the three human ADAR proteins, ADAR1 is responsible for the majority of A-to-I editing of dsRNA outside the ...
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Absence of 5' methylguanosine cap in postreplicative genes' transcripts of Vaccinia virus
abstrakt v konferenčním sborníku
open access
postprint
2023
,Czech Chemical Society Symposium Series
,21
(5)
The Vaccinia virus (VACV) played a pivotal role in the discovery of the 5' mRNA. Over the past decades, VACV investigation has contributed extensively to understanding the mechanism behind 5' mRNA cap synthesis. ...
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Blood parasites (Trypanosoma, Leucocytozoon, Haemoproteus) in the Eurasian sparrowhawk (Accipiter nisus): diversity, incidence and persistence of infection at the individual level
původní článek
open access
vydavatelská verze
2023
,BioMed Central
,Parasites & Vectors
,16
(1)
Background :A high prevalence of parasites may result from life-long persistence of infection or from high reinfection rates. We have studied blood parasites in a breeding population of the accipitrid raptor, Eurasian ...
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Same data, different conclusions: Radical dispersion in empirical results when independent analysts operationalize and test the same hypothesis
původní článek
open access
vydavatelská verze
2021
,Organizational Behavior and Human Decision Processes
,165
(1)
In this crowdsourced initiative, independent analysts used the same dataset to test two hypotheses regarding the effects of scientists' gender and professional status on verbosity during group meetings. Not only the analytic ...
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Genetic analysis challenges the presence of Ixodes inopinatus in Central Europe: Development of a multiplex PCR to distinguish I. inopinatus from I. ricinus
původní článek
open access
vydavatelská verze
2023
,Parasites & Vectors
,16
(1)
Background Ixodes ricinus is an important vector of several pathogens, primarily in Europe. Recently, Ixodes inopinatus was described from Spain, Portugal, and North Africa and then reported from several European countries. ...
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Exploring the molecular mechanisms used by human BK polyomavirus to activate immune responses in "reservoir cells"
abstrakt v konferenčním sborníku
open access
vydavatelská verze
2023
,Czech Chemical Society Symposium Series
,21
(5)
At present, the Polyomaviridae family contains 14 human polyomaviruses (PyVs), among the most important are Merkel cell polyomavirus (MCPyV), the etiological agent of 80% of Merkel cell carcinomas, JCPyV and BKPyV causing ...
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Characterization of a human placental clearance system to regulate serotonin levels in the fetoplacental unit
původní článek
open access
vydavatelská verze
2023
,Reproductive Biology and Endocrinology
,21
(1)
Background Serotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated levels of 5-HT in the fetoplacental unit are critical for proper placental ...
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TET protein inhibitors: Potential and limitations
přehledový článek
open access
vydavatelská verze
2023
,Biomedicine & Pharmacotherapy
,166
(October)
TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene expression. Dysregulation of their activity is associated with many serious pathogenic states such as oncological diseases. ...
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Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase
původní článek
open access
vydavatelská verze
2023
,eLife
,12
(July)
The activation of Src kinase in cells is strictly controlled by intramolecular inhibitory interactions mediated by SH3 and SH2 domains. They impose structural constraints on the kinase domain holding it in a catalytically ...
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Double perovskite Cs2AgBiBr6 radiation sensor: synthesis and characterization of single crystals
původní článek
open access
vydavatelská verze
2022
,Journal of Materials Science [online]
,57
(4)
Single crystals of lead-free halide double perovskite Cs(2)AgBiBr(6) sensor material manifest a remarkable potential for application in radiation detection and imaging. In this study, the purity and crystallinity of ...
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HBV-induced microenvironment reduces pDC response to TLR7/9 stimulation
abstrakt v elektronické podobě
open access
vydavatelská verze
2023
Hepatitis B virus (HBV) is an infectious agent that causes acute hepatitis, but can also lead to chronic inflammation, and, consequently, to hepatocellular carcinoma. HBV is described as "stealth virus", since it avoids ...
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Clinical Experience with Autofluorescence Guided Oral Squamous Cell Carcinoma Surgery
původní článek
open access
vydavatelská verze
2023
,Diagnostics
,13
(20)
In our study, the effect of the use of autofluorescence (Visually Enhanced Lesion Scope-VELscope) on increasing the success rate of surgical treatment in oral squamous carcinoma (OSCC) was investigated. Our hypothesis was ...
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Carl Schmitt and Democratic Backsliding
původní článek
embargo
aktualizovaná vydavatelská verze
2023
,Contemporary Political Theory
,22
(3)
This Critical Exchange suggests that Schmittian inspirations abound in countries that experience democratic backsliding. Sometimes, Schmitt's ideas are used explicitly, but more often they are implicit in the actions of ...
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Carl Schmitt and Democratic Backsliding
původní článek
embargo
vydavatelská verze
2023
,Contemporary Political Theory
,22
(3)
This Critical Exchange suggests that Schmittian inspirations abound in countries that experience democratic backsliding. Sometimes, Schmitt's ideas are used explicitly, but more often they are implicit in the actions of ...
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Acute Effects of Isometric Conditioning Activity on the Viscoelastic Properties of Muscles and Sprint and Jumping Performance in Handball Players
původní článek
omezený přístup
vydavatelská verze
2023
,Journal of Strength and Conditioning Research
,37
(7)
Krzysztofik, M, Spieszny, M, Trybulski, R, Wilk, M, Pisz, A, Kolinger, D, Filip-Stachnik, A, and Stastny, P. Acute effects of isometric conditioning activity on the viscoelastic properties of muscles and sprint and jumping ...
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Sleep quality and sleep routines as mediators of stressors and life satisfaction in Czech university students: a structural equation model
původní článek
embargo
vydavatelská verze
2023
,Frontiers in Psychology
,2023
(14)
Introduction: Sleep is especially important to overall well-being. Some aspects of sleep have been well documented, for example sleep quantity and its effect on well-being, but the value of a consistent sleep routine remains ...
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Reliability of the saliva self-sampling with and without supervision
původní článek
embargo
vydavatelská verze
2023
,Acta Universitatis Carolinae. Kinanthropologica
,59
(1)
One of the least invasive sampling methods suitable for self-sampling is saliva spitting. The aim of this study is to evaluate the suitability of saliva self-sampling for unsupervised testing. Two self-sampling strategies ...
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Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia
původní článek
open access
vydavatelská verze
2023
,Nature Communications
,14
(1)
High hyperdiploid acute lymphoblastic leukemia (HeH ALL), one of the most common childhood malignancies, is driven by nonrandom aneuploidy (abnormal chromosome numbers) mainly comprising chromosomal gains. In this study, ...
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Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome
původní článek
open access
vydavatelská verze
2023
,Nature Communications
,14
(1)
Neutrophilic inflammation is a hallmark of many monogenic autoinflammatory diseases; pathomechanisms that regulate extravasation of damaging immune cells into surrounding tissues are poorly understood. Here we identified ...
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STING agonists induce robust cytokine secretion and rapid monocyte cell death in peripheral blood mononuclear cells
abstrakt v elektronické podobě
open access
postprint
2023
The cyclic-GMP-AMP synthase - stimulator of interferon genes (cGAS-STING) pathway plays a central role in recognition of the double-stranded DNA in cytoplasm, a sign of cell damage or infection. Upon activation, the pathway ...


















